Artery Research

Volume 24, Issue C, December 2018, Pages 94 - 94

P55 EFFECTS OF CAROTID PRESSURE WAVEFORM OBTAINED IN DIFFERENT WAYS ON THE RESULTS OF WAVE SEPARATION, WAVE INTENSITY AND RESERVOIR PRESSURE ANALYSIS

Authors
Nicole Di Lascio1, Vincenzo Gemignani1, Rosa Maria Bruno2, Elisabetta Bianchini1, Martina Francesconi2, Francesco Stea1, Lorenzo Ghiadoni2, Francesco Faita1
1Institute of Clinical Physiology, CNR, Pisa, Italy
2Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.108How to use a DOI?
Abstract

Purpose/Background/Objectives: Recently great attention has been placed on innovative cardiovascular biomarkers obtained from wave separation (WS), wave intensity analysis (WIA) and the reservoir-wave (RW) concept. Pressure waveforms needed to implement these techniques can be obtained in different ways. Aim of this study was to evaluate differences in WS, WIA and RW parameters obtained deriving pressure curves in different ways.

Methods: Twenty-two individuals (49 ± 17 years, 59% males) were examined. Common carotid blood flow waveforms were obtained from Pulsed-Wave Doppler images. Carotid pressure waveforms were obtained in four different ways: 1) standard method, i.e., with applanation tonometry; 2) linear scaling from ultrasound (US)-derived diameter curve; 3) exponential scaling from US-derived diameter curve; 4) linear scaling from an accelerometric-derived diameter signal. In each case, reflection magnitude (RM) and reflection index (RI) were obtained from WS. The amplitude of the first positive peak (W1), of the second positive peak (W2) and of the negative one (Wb) were calculated from WIA; the maximum of the reservoir (maxPr) and the excess (maxPex) pressure were achieved from RW.

Results: According to the intra-class coefficient values, the agreement between the standard method and all the others was excellent in case of RM, RI, maxPrand maxPex(0.82–0.97), while reached only a fair/good level in case of W1, W2and Wb(0.44–0.82).

Conclusions: The use of alternative carotid pressure waveforms does not influence the cardiovascular parameters obtained by WS and RW, while those derived by WIA are affected by the carotid pressure curve employed.

Open Access
This is an open access article distributed under the CC BY-NC license.

Journal
Artery Research
Volume-Issue
24 - C
Pages
94 - 94
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.108How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Nicole Di Lascio
AU  - Vincenzo Gemignani
AU  - Rosa Maria Bruno
AU  - Elisabetta Bianchini
AU  - Martina Francesconi
AU  - Francesco Stea
AU  - Lorenzo Ghiadoni
AU  - Francesco Faita
PY  - 2018
DA  - 2018/12/04
TI  - P55 EFFECTS OF CAROTID PRESSURE WAVEFORM OBTAINED IN DIFFERENT WAYS ON THE RESULTS OF WAVE SEPARATION, WAVE INTENSITY AND RESERVOIR PRESSURE ANALYSIS
JO  - Artery Research
SP  - 94
EP  - 94
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.108
DO  - 10.1016/j.artres.2018.10.108
ID  - DiLascio2018
ER  -