Artery Research

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Volume 24, Issue C, December 2018, Pages 93 - 93

P51 NON-CONTACT MEASUREMENT OF LOCAL CAROTID AND CAROTID-FEMORAL PULSE WAVE VELOCITY BY LASER DOPPLER VIBROMETRY: VALIDATION OF A NEW DEVICE AGAINST REFERENCE TECHNIQUES IN HYPERTENSIVE PATIENTS

Authors
Louise Marais1, Soren Aasmul2, Roel Baets3, Mirko De Melis2, Stephen E. Greenwald4, Hakim Khettab1, Yanlu Li3, Frits Prinzen5, Koen Reesink5, Patrick Segers6, Pierre Boutouyrie1
1PARCC, INSERM U970, Georges Pompidou European Hospital, Paris, France
2Medtronic Bakken Research Center, Maastricht, the Netherlands
3Photonics Research Group, INTEC, Ghent University, IMEC, Ghent, Belgium
4Blizard Institute, Queen Mary University of London, London, UK
5CARIM, Maastricht University Medical Center, Maastricht, the Netherlands
6bioMMeda – Institute Biomedical Technology, Ghent University, Ghent, Belgium
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.104How to use a DOI?
Abstract

Objective: PWV measurement devices are technically demanding, expensive and prone to artefacts, thus limiting the measurement of arterial stiffness in primary care. The CARDIS consortium developed a non-contact device based on the detection of skin movements induced by arterial pulses through a laser Doppler vibrometer (CARDIS-LDV). Our objective is to validate CARDIS-LDV against reference techniques.

Methods: This study sponsored by INSERM will include 100 essential hypertensives, males and females, grade I–III, aged 18–80. The CARDIS-LDV comprises two rows of 6 laser beams spaced 5 mm (2.5 cm wide). These rows are either situated 2.5 cm apart for local PWV measurement or can be split in two for carotid to femoral measurement. To calculate PWV, the time delay between the two rows is assessed by analyzing the corresponding skin displacement signals. Aortic stiffness is measured by the Sphygmocor® technique and carotid stiffness by echotracking ArtLab®

Results: Measurements by CARDIS-LDV are easy and fast to perform. A simple palpation of pulse is enough to position the device and obtain good signals thanks to the 6-beam array. Figure 1 shows an example of a carotid-femoral recording on a healthy volunteer (age 28). PWV is 5.88 ± 0.30 m/s using the maximum of 1st derivative method, compared with 5.96 ± 0.40 m/s with tonometry. Data on larger sample size will be presented at the meeting.

Conclusion: CARDIS-LDV is a promising technique to assess arterial stiffness; we expect to demonstrate its good agreement with reference techniques and that it improves the screening of cardiovascular risk in large populations.

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This is an open access article distributed under the CC BY-NC license.

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Journal
Artery Research
Volume-Issue
24 - C
Pages
93 - 93
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.104How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Louise Marais
AU  - Soren Aasmul
AU  - Roel Baets
AU  - Mirko De Melis
AU  - Stephen E. Greenwald
AU  - Hakim Khettab
AU  - Yanlu Li
AU  - Frits Prinzen
AU  - Koen Reesink
AU  - Patrick Segers
AU  - Pierre Boutouyrie
PY  - 2018
DA  - 2018/12/04
TI  - P51 NON-CONTACT MEASUREMENT OF LOCAL CAROTID AND CAROTID-FEMORAL PULSE WAVE VELOCITY BY LASER DOPPLER VIBROMETRY: VALIDATION OF A NEW DEVICE AGAINST REFERENCE TECHNIQUES IN HYPERTENSIVE PATIENTS
JO  - Artery Research
SP  - 93
EP  - 93
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.104
DO  - 10.1016/j.artres.2018.10.104
ID  - Marais2018
ER  -