Artery Research

Volume 24, Issue C, December 2018, Pages 84 - 84

P16 PULSE WAVE VELOCITY AND ITS ASSOCIATION WITH FIRST CARDIOVASCULAR EVENTS IN A PORTUGUESE HYPERTENSIVE SAMPLE

Authors
Clarinda Neves1, 2, 3, Joana Ricardo Pires4, Verónica Ribau4, José Mesquita Bastos4, 5, 6
1Clarinda Neves, Portugal
2Centro Hospitalar Baixo Vouga, Aveiro, Portugal
3Departamento de Ciências Médicas, Universidade de Aveiro, Portugal
4Centro Hospitalar do Baixo Vouga, Aveiro, Portugal
5ESSUA, Universidade de Aveiro, Portugal
6CINTESIS, Portugal
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.069How to use a DOI?
Abstract

Objective: Pulse Wave Velocity (PWV) is considered a marker of cardiovascular (CV) risk prognosis. The objective was to evaluate the association of PWV, other features and CV events in a sample of hypertensive patients.

Design and method: We studied 314 hypertensive patients without previous CV events evaluated by PWV in a Portuguese average-size hospital, through its descriptive and survival analysis.

Results: Of the 314 patients (51% male) ageing 54.0 ± 14.2 years, 31.5% had resistant hypertension, 26.8% were diabetic, 66.6% had hyperlipidaemia, the average body mass index was 28.3 kg m−2, and 16.6% were active smoker. Through a follow-up of 2.1 ± 2.2 years, 28 patients (8.9%) had a CV event. Comparison of the patients with PWV ≤ 10 ms−1 and the patients with PWV >10 ms−1, showed statistical significance for age (64.3 ± 10.5 vs 50.2 ± 13.4 years, p < 0.0001), casual systolic blood pressure (137.4 ± 16.3 mmHg vs 154.4 ± 21.4 mmHg, p < 0.0001), PWV (7.9 ± 1,2 ms−1 vs 12.2 ± 1.9 ms−1, p < 0.0001) left ventricular hypertrophy (193,3 ± 58.6 vs 235,8 ± 65.1, p < 0.01) and left auricular volume (19,9 ± 3.9 vs 23.3 ± 5.8, p < 0.002). Patients with PWV>10ms−1, 77,3% had left ventricular hypertrophy (p < 0.004) and 70% had left auricular enlargement (p < 0.08). In the survival analysis, the Kaplan Meier curve showed a worse prognosis for CV events with PWV > 10 ms−1 (log rank 6.0, p < 0,014).

Conclusions: Higher PWV indicating worse artery damage is associated with end organ damage like left ventricular hypertrophy and left auricular enlargement. In patients with no previous CV events, PWV>10 ms−1 is an indicator for worse prognosis for CV events.

Open Access
This is an open access article distributed under the CC BY-NC license.

Journal
Artery Research
Volume-Issue
24 - C
Pages
84 - 84
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.069How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Clarinda Neves
AU  - Joana Ricardo Pires
AU  - Verónica Ribau
AU  - José Mesquita Bastos
PY  - 2018
DA  - 2018/12/04
TI  - P16 PULSE WAVE VELOCITY AND ITS ASSOCIATION WITH FIRST CARDIOVASCULAR EVENTS IN A PORTUGUESE HYPERTENSIVE SAMPLE
JO  - Artery Research
SP  - 84
EP  - 84
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.069
DO  - 10.1016/j.artres.2018.10.069
ID  - Neves2018
ER  -