Artery Research

Volume 24, Issue C, December 2018, Pages 83 - 83

P13 VASCULAR AND MUSCLE DETERIORATION IN OLDER OUTPATIENTS

Authors
Lisanne Tap, Linda Kannegieter, Antine Flikweert, Francesco Mattace Raso
Section of Geriatric Medicine, Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.066How to use a DOI?
Abstract

Background: Vascular and muscle deterioration are age-related processes, which both have a major impact on health and might share common predisposing factors and mechanisms. We investigated the possible association between aortic stiffness and physical performance in older outpatients.

Methods: Aortic stiffness was non-invasively measured as aortic pulse wave velocity (aPWV) by the Mobil-o-Graph. Physical performance was assessed by the (a) hand grip strength and (b) usual gait speed on 5-meter course. Low grip strength was <20 kg for women and <30 kg for men. Slow gait speed was defined as ≤0.8 m/s. Mean values of aPWV were investigated in patients according to their physical performance.

Results: We included 240 consecutive outpatients. Mean age was 77.6 (±7.1) years, mean aPWV was 12.0 (±1.7)m/s. Low hand grip strength was found in 43.3%, slow gait speed in 37.1%. Compared to the normal physical performance group, patients with low grip strength were 5.3 years older (p < 0.001) and patients with slow gait speed were 2.9 years older (p = 0.002). Patients with normal grip strength had lower aPWV than patients with low grip strength (11.58 vs 12.6, p < 0.001). Patients with normal gait speed had lower aPWV than patients with slow gait speed (11.81 vs 12.3, p = 0.042). After adjustments for age, sex and mean arterial pressure, no differences were found in aPWV between patients with a normal and low physical performance.

Conclusion: Higher aortic stiffness is associated with lower physical performance in older outpatients. However, age plays a crucial role in this relationship.

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Journal
Artery Research
Volume-Issue
24 - C
Pages
83 - 83
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.066How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Lisanne Tap
AU  - Linda Kannegieter
AU  - Antine Flikweert
AU  - Francesco Mattace Raso
PY  - 2018
DA  - 2018/12/04
TI  - P13 VASCULAR AND MUSCLE DETERIORATION IN OLDER OUTPATIENTS
JO  - Artery Research
SP  - 83
EP  - 83
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.066
DO  - 10.1016/j.artres.2018.10.066
ID  - Tap2018
ER  -