4.7 THE EFFECT OF TRANSCATHETER AORTIC VALVE IMPLANTATION ON AORTIC STIFFNESS AND HEMODYNAMICS

Vasiliki Gardikioti; D. Terentes-Printzios; C. Vlachopoulos; K. Toutouzas; M. Xanthopoulou; G. Benetos; G. Latsios; V. Penesopoulou; V. Tsigkou; G. Siasos; E. Vavuranakis; D. Tousoulis

doi:10.1016/j.artres.2018.10.046

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Volume 24, Issue C, December 2018, Pages 77 - 77

4.7 THE EFFECT OF TRANSCATHETER AORTIC VALVE IMPLANTATION ON AORTIC STIFFNESS AND HEMODYNAMICS

Authors

Vasiliki Gardikioti¹^{, 2}, D. Terentes-Printzios², C. Vlachopoulos², K. Toutouzas², M. Xanthopoulou², G. Benetos², G. Latsios², V. Penesopoulou², V. Tsigkou², G. Siasos², E. Vavuranakis², D. Tousoulis²

¹1st Department of Cardiology, Hippokration General Hospital of Athens, Medical School, National and Kapodistrian University of Athens, Greece

²Hippokration Hospital, University of Athens, 1st Department of Cardiology, Athens, Greece

Available Online 4 December 2018.

DOI: 10.1016/j.artres.2018.10.046 How to use a DOI?
Abstract: Purpose/Background/Objectives: Aortic stiffness and central hemodynamics are established vascular biomarkers. Transcatheter aortic valve implantation (TAVI) is a promising new technique for the treatment of aortic valve stenosis in elderly patients. We examined the effect of TAVI on the elastic properties of the aorta and on central hemodynamics.

Methods: We included fifty patients (mean age 80.7 ± 8.3 years, 27 male) with symptomatic aortic stenosis treated by TAVI. In measurements prior and acutely after the procedure, carotid-femoral pulse wave velocity (cfPWV) and brachial-ankle pulse wave velocity (baPWV) were used as indicators of arterial stiffness. Aortic pressures and aortic augmentation index corrected for heart rate [AIx@75] were used to assess aortic hemodynamics.

Results: There was a statistically significant increase in measurements of arterial stiffness (7.7 ± 1.5 vs 8.3 ± 1.9 m/s for cfPWV and 1931 ± 577 vs. 2469 ± 682 cm/s with p = 0.006 and p0.05). Peripheral pulse pressure (p = 0.047) increased significantly and peripheral DBP (p = 0.05) decreased significantly.

Conclusions: Our study led to the observation that patients undergoing TAVI present with an increase in arterial stiffness in the acute phase after the procedure, accompanied by an improvement of wave reflections. At the same time, a dissociation between aortic and peripheral BP after TAVI was observed, which may indicate important clinical value.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 24 - C
Pages: 77 - 77
Publication Date: 2018/12/04
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2018.10.046 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

Cite this article

ris enw bib

TY  - JOUR
AU  - Vasiliki Gardikioti
AU  - D. Terentes-Printzios
AU  - C. Vlachopoulos
AU  - K. Toutouzas
AU  - M. Xanthopoulou
AU  - G. Benetos
AU  - G. Latsios
AU  - V. Penesopoulou
AU  - V. Tsigkou
AU  - G. Siasos
AU  - E. Vavuranakis
AU  - D. Tousoulis
PY  - 2018
DA  - 2018/12/04
TI  - 4.7 THE EFFECT OF TRANSCATHETER AORTIC VALVE IMPLANTATION ON AORTIC STIFFNESS AND HEMODYNAMICS
JO  - Artery Research
SP  - 77
EP  - 77
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.046
DO  - 10.1016/j.artres.2018.10.046
ID  - Gardikioti2018
ER  -

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