P14.03 IS THERE A SHIFT OF THE REFLECTION POINT FROM PERIPHERAL TO CENTRAL ARTERIES WITH AGE IN HYPERTENSIVE PATIENTS?

P. Forcada; D. Olano; S. Gonzalez; S. Obregon; J. Chiavaut Svane; C. Castelaro; E. Cavanagh; F. Inserra; C. Kotliar

doi:10.1016/j.artres.2010.10.144

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Volume 4, Issue 4, December 2010, Pages 186 - 186

P14.03 IS THERE A SHIFT OF THE REFLECTION POINT FROM PERIPHERAL TO CENTRAL ARTERIES WITH AGE IN HYPERTENSIVE PATIENTS?

Authors

P. Forcada¹, D. Olano², S. Gonzalez¹, S. Obregon¹, J. Chiavaut Svane¹, C. Castelaro¹, E. Cavanagh², F. Inserra², C. Kotliar¹

¹Hospital Universitario Austral, Pilar, Argentina

²Universidad Austral, Pilar, Argentina

Available Online 2 December 2010.

DOI: 10.1016/j.artres.2010.10.144 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

Introduction: Stiffening of arteries with age has been extensively described but this proccess has not been fully characterized at different levels of the arterial tree.

Aim: To evaluate the behavior of arterial function parameters according to age.

Methods: We screened 3277 p. derived for non-invasive vascular evaluation (NIVE) (Dec 2006/Dec 2009). NIVE comprised: IMT; PWV and FMD; atherosclerotic plaque (AP) characterization; Aortic and Peripheral pulse pressure(CPP and PPP) and Augmentation indexes (CAix and PAix). After applying exclusion criteria (age >65; diabetes mellitus, secondary HTN, previous CV events/secondary prevention) and the availability of data of PWV, CAix and PAix 1503 p. were included and analyzed according age (from 20 to 80 years old in deciles).

Results: We observed a progressive increase of all the arterial parameters with age (from 20 to 80 y.o.): PWV (8,8± 2 to 14± 4 m/sec), CPP (from 43± 15 to 59± 17mmHg), PPP (from 49± 12 to 58± 13 mmHg), CAix (from 12 to 36%) and PAix (from − 40% to 13%).

In the 50^th decade a cross of values of PP (Central >Peripheral) and increase of PAix was observed suggesting a shift of the reflection point from peripheral to central arteries.

Conclusions: The stiffening of central arteries with age is associated with a progressive shift of the reflection point from peripheral to the central arteries and the loss of the pulse amplification in peripheral arteries.

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Journal: Artery Research
Volume-Issue: 4 - 4
Pages: 186 - 186
Publication Date: 2010/12/02
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2010.10.144 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

Cite this article

ris enw bib

TY  - JOUR
AU  - P. Forcada
AU  - D. Olano
AU  - S. Gonzalez
AU  - S. Obregon
AU  - J. Chiavaut Svane
AU  - C. Castelaro
AU  - E. Cavanagh
AU  - F. Inserra
AU  - C. Kotliar
PY  - 2010
DA  - 2010/12/02
TI  - P14.03 IS THERE A SHIFT OF THE REFLECTION POINT FROM PERIPHERAL TO CENTRAL ARTERIES WITH AGE IN HYPERTENSIVE PATIENTS?
JO  - Artery Research
SP  - 186
EP  - 186
VL  - 4
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2010.10.144
DO  - 10.1016/j.artres.2010.10.144
ID  - Forcada2010
ER  -

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