Artery Research

Volume 8, Issue 4, December 2014, Pages 150 - 150

P7.10 PRE-TREATMENT AORTIC PULSE PRESSURE AS A POSSIBLE PREDICTOR OF FUTURE VISIT-TO-VISIT SYSTOLIC BLOOD PRESSURE VARIABILITY

Authors
E. Troitskaya, Y. Kotovskaya, Z. Kobalava
Peoples’ Friendship University of Russia, Moscow, Russia
Available Online 4 November 2014.
DOI
10.1016/j.artres.2014.09.172How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Background: Visit-to-visit systolic blood pressure variability (SBPV) in treated hypertensive patients may have impact on prognosis and it stimulates searching for its predictors. The aim of the study was to evaluate SBPV and its predictors in patients with controlled AH.

Methods: 52 pts(20 men, age58,9±9,0yrs;4 smokers;6 diabetics) with uncomplicated AH were treated to target BP<140/90mmHg with combination of RAAS-inhibitor and amlodipine for 1yr. Baseline BP was 163,4±8,1/100,9±4,2mmHg; achieved-123,7±9,7/76,8±6,7mmHg. SBPV was calculated as SD for 5 visits during 8 months after target BP achievement. Central BP and pulse wave velocity (PWV) were measured before treatment initiation and at the end of the study. p<0,05 was considered significant.

Results: SBPV after achievement of target BP varied from 1,79 mmHg to 16,79 mmHg (tertile I < 5,38; II 5,38 – 7,78; III > 7,78 mmHg). The groups were similar by age (I 56,6±8,94, II 59,4±9, III 60,7±9,1 yrs, p>0,05), gender, metabolic risk factors, baseline and achieved BP. Higher SBPV was associated with higher baseline central PP: for tertI 47,2±10,6, tertII 55,6±11, tertIII 51,1±11,5 mmHg (p<0,05 vs tertI). Number of patients with baseline central PP>50 mmHg was higher in the tertII(76,5%vs50% in tertII and 41%in tertI,Pearson’s χ2=2,1; <0,05) No significant difference was found for Aix@75HR(23,3±11,2 vs 23,2±13,4 vs 25,5±9,1% for corresponding tertiles,p>0,05) and PWV(13±1,6 vs14,2±2,2 vs12,9±1,8 m/s). No correlation was found between SBPV and any other characteristics, including baseline central PP.

Conclusion: Association between baseline central PP and SBPV after achievement of target BP confirms the role of arterial stiffness as predictor of BP variability.

Journal
Artery Research
Volume-Issue
8 - 4
Pages
150 - 150
Publication Date
2014/11/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2014.09.172How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - E. Troitskaya
AU  - Y. Kotovskaya
AU  - Z. Kobalava
PY  - 2014
DA  - 2014/11/04
TI  - P7.10 PRE-TREATMENT AORTIC PULSE PRESSURE AS A POSSIBLE PREDICTOR OF FUTURE VISIT-TO-VISIT SYSTOLIC BLOOD PRESSURE VARIABILITY
JO  - Artery Research
SP  - 150
EP  - 150
VL  - 8
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2014.09.172
DO  - 10.1016/j.artres.2014.09.172
ID  - Troitskaya2014
ER  -