P11.13 CORONARY CALCIFICATION IN YOUNG AND MIDDLE-AGED MEN WITH CORONARY ARTERY DISEASE
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- 10.1016/j.artres.2011.10.169How to use a DOI?
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Objective: To compare the presence and extent of coronary calcification in young and middle-aged patients with new onset coronary artery disease (CAD) with matched controls without a history of CAD.
Methods: A total of 50 men aged 28 to 50 (mean age: 43 ± 5) years with angiographically proven CAD underwent multislice computed tomography (MSCT) studies. Those with arterial hypertension, diabetes mellitus or marked hypercholesterolemia (LDL cholesterol >4.5 mmol/l) were excluded from the study. Coronary calcification wAS quantified using the Agatston score (CCS). The results were compared with a group of 30 controls without CAD, matched for sex, age, and risk factors.
Results: Calcifications were present in 86% of patients with CAD and in 16.7% of controls (p <0.001). The mean (SD) CCS was 285±314 in the CAD patients versus 31±129 in the controls (p <0.001). Absence of calcium, CCS of 1 to 99 (mild), 100 to 399 (moderate), and ≥400 (severe) was observed in 7 (14%), 16 (32%), 15 (30%), and 12 (24%) of the patients with CAD, and in 25 (84%), 3 (10%), 1 (3%), and 1 (3%) of the patients without CAD, respectively. Extent of coronary calcification in the CAD patients was not related to the severity of CAD.
Conclusion: In young and middle-aged patients with new onset CAD the presence and extent of coronary calcification is significantly greater than in matched controls.
Cite this article
TY - JOUR AU - S.G. Kozlov AU - T.V. Balachonova AU - H.A. Machmudova AU - M.B. Belkind PY - 2011 DA - 2011/11/29 TI - P11.13 CORONARY CALCIFICATION IN YOUNG AND MIDDLE-AGED MEN WITH CORONARY ARTERY DISEASE JO - Artery Research SP - 195 EP - 196 VL - 5 IS - 4 SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2011.10.169 DO - 10.1016/j.artres.2011.10.169 ID - Kozlov2011 ER -