P4.08 BIOMECHANICAL STUDY OF ANEURYSM RUPTURE
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- 10.1016/j.artres.2011.10.053How to use a DOI?
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The rupture of aortic aneurysms is a catastrophic event that represents a major public health issue. It has received a large interest from the scientific community. However, only limited research has provided quantitative values of mechanical stresses that may assess the risks of rupture of aneurysms [1].
In this study we have applied an imaging approach for measuring the deformations of the aneurysmal tissue tested in a biaxial inflation test [2]. The tissues have been taken from the thoracic ascending aorta of 6 diseased patients operated for aneurysm treatment by conventional surgery at the University Hospital of Saint-Etienne, France.
Quantitative values of ultimate stresses are reported in Tab. 1. Rupture is anisotropic, but primarily induced by axial stresses. Moreover, it is observed that rupture in aneurysms is preceded by a local weakening of the mechanical properties of the tissue, especially in the intima and media layers which are more fragile, and that these effects announcing a pending rupture can be detected by advanced imaging techniques. Our investigations continue in that sense for proposing novel diagnosis methodologies based on these observations.
Patient gender | M | M | M | M | M | M |
---|---|---|---|---|---|---|
Age | 81 | 81 | 68 | 69 | 76 | 76 |
Type | adventitia | media | media | media | media | adventitia |
Stress at rupture (MPa) | 0.6257 | 0.3719 | 0.3686 | 0.4107 | 0.3483 | 1.0522 |
Quantitative values of ultimate stress measured at rupture
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TY - JOUR AU - J. Kim AU - A. Romo AU - P. Badel AU - A. Duprey AU - J.N. Albertini AU - J.P. Favre AU - S. Avril PY - 2011 DA - 2011/11/29 TI - P4.08 BIOMECHANICAL STUDY OF ANEURYSM RUPTURE JO - Artery Research SP - 161 EP - 161 VL - 5 IS - 4 SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2011.10.053 DO - 10.1016/j.artres.2011.10.053 ID - Kim2011 ER -