Artery Research

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Volume 25, Issue 3-4, December 2019, Pages 101 - 105

Central Hemodynamic Parameters are Altered in Resistant Hypertensive Individuals

Authors
João Marcos de Menezes Zanatta, Fábio dos Santos Ricardi, Elizabeth do Espírito Santo Cestário, Tatiana Azevedo, Jéssica Rodrigues Uyemura, Luciana Neves Cosenso-Martin, Juan Carlos Yugar-Toledo, José Fernando Vilela-Martin*
Internal Medicine Department, State Medical School, Sao Jose do Rio Preto (FAMERP), Sao Paulo, Brazil
*Corresponding author. Email: vilelamartin@uol.com.br
Corresponding Author
José Fernando Vilela-Martin
Received 30 November 2019, Accepted 30 November 2019, Available Online 17 December 2019.
DOI
10.2991/artres.k.191203.002How to use a DOI?
Keywords
Hypertension; resistant hypertension; sodium; arterial stiffness
Abstract

Background: Systemic arterial hypertension (SAH) is one of the major risk factors related to the development of cardiovascular diseases (CVD). Sodium intake is linked to elevated blood pressure and can be estimated by 24-h urinary sodium excretion. The objective of this study was to correlate 24 h urinary sodium excretion, blood pressure and arterial stiffness (AS) parameters in hypertensive individuals.

Methods: We evaluated 53 patients who underwent in-office 24-h blood pressure tests and AS parameters using the Mobil-O-Graph® equipment. The patients were divided into controlled hypertensive and resistant hypertensive. Unpaired t-test was performed with significance at p < 0.05.

Results: Mean age was 64.32 years; weight 77.56 kg; height 1.61 m; and BMI of 29.68 kg/m2. Resistant hypertensive patients (25 subjects) have systolic blood pressure (SBP) (p < 0.0001), diastolic blood pressure (DBP) (p = 0.004), 24 h SBP (p < 0.0001), 24 h DBP (p = 0.002), pulse pressure (PP) (p < 0.0001), central systolic blood pressure (cSBP) (p = 0.0003) and central diastolic blood pressure (cDBP) (p = 0.021) higher than controlled hypertensive patients (28 subjects).

Conclusion: Peripheral and central arterial pressures are higher in resistant hypertensive than in controlled hypertensive. Sodium excretion is unrelated to hemodynamic variables. Age is related to the elevation of central pressure and pulse wave velocity.

Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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<Previous Article In Issue
Next Article In Issue>
Journal
Artery Research
Volume-Issue
25 - 3-4
Pages
101 - 105
Publication Date
2019/12/17
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.2991/artres.k.191203.002How to use a DOI?
Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - JOUR
AU  - João Marcos de Menezes Zanatta
AU  - Fábio dos Santos Ricardi
AU  - Elizabeth do Espírito Santo Cestário
AU  - Tatiana Azevedo
AU  - Jéssica Rodrigues Uyemura
AU  - Luciana Neves Cosenso-Martin
AU  - Juan Carlos Yugar-Toledo
AU  - José Fernando Vilela-Martin
PY  - 2019
DA  - 2019/12/17
TI  - Central Hemodynamic Parameters are Altered in Resistant Hypertensive Individuals
JO  - Artery Research
SP  - 101
EP  - 105
VL  - 25
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.191203.002
DO  - 10.2991/artres.k.191203.002
ID  - Zanatta2019
ER  -