Artery Research

Volume 3, Issue 3, September 2009, Pages 97 - 97

10. THE USEFULNESS OF ESTIMATED CAROTID SYSTOLIC BLOOD PRESSURE USING FORM PWV/ABI IN BLOOD PRESSURE LOWERING THERAPY

Authors
Hisayo Yasuda, Kei Kamide, Yoshio Iwashima, Takeshi Horio, Hidenori Nishida, Fumiki Yoshihara, Satoko Nakamura, Yuhei Kawano
Division of Hypertension and Nephrology, National Cardiovascular Center
Available Online 31 October 2009.
DOI
10.1016/j.artres.2009.06.022How to use a DOI?
Abstract

Background: Central systolic blood pressure (central-SBP) can be estimated noninvasively and antihypertensive drugs may exert different effects on central-SBP. We investigated the usefulness of carotid systolic blood pressure (carotid-SBP) estimated by form PWV/ABI in blood pressure lowering therapy.

Methods: We evaluated pulse wave velocity, carotid augmentation index (AI), carotid-SBP in 329 patients (301 hypertensives, 172 men, 65±12 yeasrs old) using form PWV/ABI. Antihypertensive drugs were evaluated in those patients.

Results: Mean brachial blood pressure (b-SBP) was 136±21 mmHg and carotid-SBP was 147±25 mmHg. We determined delta-SBP as carotid-SBP - b-SBP, and we divided the subjects into group A (delta-SBP<0mmHg) and group B (delta-SBP>0mmHg). The number of group A was 22 patients and that of group B was 307 patients. There were no differences of mean age between these two groups. Although b-SBP of group A (137±21 mmHg) was similar to that of group B (136±21 mmHg), b-diastolic BP of group A (83±12mmHg) was different from that of group B (77±13 mmHg, p=0.0456). Carotid AI of group A (13±14%) is lower than that of group B (23±18%, p=0.0160). The evaluation of the effect of antihypertensive agents showed that Ca antagonists, angiotensin receptor blockers, angiotensin converting enzyme inhibitors and diuretics did not affect delta-SBP significantly. However, those who had β blockers or blockers showed higher delta-SBP compared to those who without these drugs.

Conclusion: Estimation of carotid-SBP using form PWV/ABI is useful for the evaluation of the effects of antihypertensive drugs on brachial and central BPs.

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Journal
Artery Research
Volume-Issue
3 - 3
Pages
97 - 97
Publication Date
2009/10/31
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2009.06.022How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Hisayo Yasuda
AU  - Kei Kamide
AU  - Yoshio Iwashima
AU  - Takeshi Horio
AU  - Hidenori Nishida
AU  - Fumiki Yoshihara
AU  - Satoko Nakamura
AU  - Yuhei Kawano
PY  - 2009
DA  - 2009/10/31
TI  - 10. THE USEFULNESS OF ESTIMATED CAROTID SYSTOLIC BLOOD PRESSURE USING FORM PWV/ABI IN BLOOD PRESSURE LOWERING THERAPY
JO  - Artery Research
SP  - 97
EP  - 97
VL  - 3
IS  - 3
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2009.06.022
DO  - 10.1016/j.artres.2009.06.022
ID  - Yasuda2009
ER  -