Proceedings of the 2nd International Conference on Sports Sciences and Health 2018 (2nd ICSSH 2018)

High Intensity Interval Training (HIIT) and Moderate Intensity Training (MIT) Against TNF-α and IL-6 levels In Rats

Authors
Mr. Hadiono, B.M. Wara Kushartanti
Corresponding Author
Mr. Hadiono
Available Online February 2019.
Keywords
HIIT, MIT, TNF-α, IL-6, Obesity
Abstract

The aim of this study was to investigate the effect of exercise with High Intensity Interval Training (HIIT) and Moderate Intensity Training (MIT) on inflammatory profile of proinflammatory cytokines TNF-α and IL-6 on the subject of obesity.This research is used 39 wistar rats of male-sex obesity. Intervention training is given for 6 weeks with frequency 4 times per week, HIIT intensity (90-100% of base line capability), MIT (60-80% of base line capability) TNF-α and IL-6 levels are obtained from blood testing with using ELISA test. Data analysis using Anova test.The results of this study showed that there were differences in levels of TNF-α HIIT with control (P = 0.003), MIT with control (P = 0.001) and no difference between HIIT group and MIT (P = 0.945). There was a difference of IL-6 levels between HIIT and control (P = 0.000), HIIT with MIT (P = 0.002), no difference in MIT group with control (P = 0.747). Exercise with the method of HIIT and MIT for 6 weeks with a frequency of 4 times per week can not create levels of TNF-α on the subject of obesity are lower as compared with sedentary groups, even the levels of TNF-α group of HIIT and MIT were significantly higher compared with the sedentary group. As for the levels of IL-6, HIIT is more effective in influencing the low IL-6 compared to MIT.

Copyright
© 2019, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2nd International Conference on Sports Sciences and Health 2018 (2nd ICSSH 2018)
Series
Advances in Health Sciences Research
Publication Date
February 2019
ISBN
978-94-6252-680-8
ISSN
2468-5739
Copyright
© 2019, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Mr. Hadiono
AU  - B.M. Wara Kushartanti
PY  - 2019/02
DA  - 2019/02
TI  - High Intensity Interval Training (HIIT) and Moderate Intensity Training (MIT) Against TNF-α and IL-6 levels In Rats
BT  - Proceedings of the 2nd International Conference on Sports Sciences and Health 2018 (2nd ICSSH 2018)
PB  - Atlantis Press
SP  - 87
EP  - 90
SN  - 2468-5739
UR  - https://www.atlantis-press.com/article/55914034
ID  - Hadiono2019/02
ER  -