Artery Research
2994 articles
Conference Abstract
P.019 CAROTID-RADIAL PULSE WAVE VELOCITY DURING THE TESTS ON REACTIVE HYPEREMIA IN PATIENTS WITH ISOLATED SYSTOLIC AND SYSTOLIC-DIASTOLIC ARTERIAL HYPERTENSION
A.A. Dzizinsky, K.V. Protasov, O.V. Fedorishina, S.G. Kuklin
Pages: 57 - 57
Conference Abstract
4.4 MIDDLE CEREBRAL ARTERY PULSATILITY IN HEART FAILURE AND PATIENTS WITH CONTINUOUS-FLOW LEFT VENTRICULAR ASSIST DEVICES
Eric Stöhr, Francesco Castagna, James Pearson, Laura Watkeys, Samuel Trocio, Oksana Zatvarska, Timothy Crimmins, Alberto Pinsino, Paolo Colombo, Melana Yuzefpolskaya, Reshad Garan, Veli Topkara, Hiroo Takayama, Koji Takeda, Yoshifumi Naka, John Cockcroft, Joshua Willey, Barry McDonnell
Pages: 57 - 57
Background: High pulsatility index (PI) in the cerebral circulation has been associated with increased prevalence of stroke (1). Interestingly, heart failure (HF) patients implanted with continuous-flow left ventricular assist devices (CF-LVADs) have increased rates of stroke despite presenting with...
Conference Abstract
5.2 AN ASSOCIATED WITH FAMILIAL HEMIPLEGIC MIGRAINE TYPE 2 MUTATION IN THE ALPHA-2 ISOFORM NA,K-ATPASE DISTURBS VASCULAR RESPONSES IN MOUSE BRAIN
Christian Staehr, Lise Hangaard, Karin Lykke-Hartmann, Elena Bouzinova, Christian Aalkjaer, Vladimir Matchkov
Pages: 57 - 57
Objectives: Migraine attack is associated with severe changes in brain perfusion vasoconstriction-induced hypoxemia during aura and rebound vasodilation in subsequent headache. Familial Hemiplegic Migraine Type 2 is associated with point mutations (including G301R) in the α2 isoform Na,K-ATPase. Heterozygote...
Conference Abstract
P.020 INTERRELATIONS BETWEEN CAROTID-RADIAL PULSE WAVE VELOCITY AND BLOOD PRESSURE MONITORING DATA IN PATIENTS WITH ISOLATED SYSTOLIC HYPERTENSION
K.V. Protasov, A.A. Dzizinsky, D.A. Sinkevich, S.G. Kuklin
Pages: 57 - 57
Conference Abstract
4.5 THE EFFECT OF LUNG FUNCTION ON BLOOD PRESSURE AND VASCULAR INDICES FROM ADOLESCENCE TO EARLY ADULTHOOD IN A MULTI-ETHNIC COHORT
Yao Lu, Harding Seeromanie
Pages: 57 - 57
Given the significance of lung function (LF) for vascular health in adulthood, there are surprisingly few studies that have examined the interrelationships of their developmental trajectories. Both develop and decline over the life course, though LF peaks in the 20s, and both predict cardiovascular events...
Conference Abstract
5.3 REVERSIBILITY OF ARTERIAL STIFFNESS AFTER KIDNEY TRANSPLANTATION: SYSTEMATIC REVIEW AND META-ANALYSIS
Aboubacar Sidibe, Catherine Fortier, Marie-Pier Desjardins, Fabrice Mac-Way, Sacha De Serres, Mohsen Agharazii
Pages: 57 - 57
Background: Chronic kidney disease is associated with increased arterial stiffness. Correction of the uremic milieu by kidney transplantation (KTx) may be improve arterial stiffness. However, results from clinical studies are not uniformly convincing. This could be related to small sample size of studies,...
Conference Abstract
P.021 DYNAMICS OF CAROTID-RADIAL PULSE WAVE VELOCITY IN OCCLUSION TEST IS RELATED TO THE TARGET-ORGANS DAMAGE IN ESSENTIAL ARTERIAL HYPERTENSION
K.V. Protasov, A.A. Dzizinsky, D.A. Sinkevich, S.G. Kuklin
Pages: 57 - 57
Conference Abstract
4.6 HIPPOCAMPAL CEREBRAL BLOOD FLOW DEPENDS ON SYSTEMIC ENDOTHELIAL FUNCTION IN INDIVIDUALS WITH MILD COGNITIVE IMPAIRMENT: THE TRAIN THE BRAIN-MIND THE VESSEL STUDY
Rosa Maria Bruno, Lorenza Pratali, Rosa Sicari, Francesco Stea, Nicoletta Berardi, Gloria Tognoni, Ubaldo Bonuccelli, Lorenzo Ghiadoni, Stefano Taddei, Danilo Scelfo, Laura Biagi, Michela Tosetti, Lamberto Maffei, Eugenio Picano
Pages: 57 - 58
Background: Dementia has been recently viewed as a predominantly vascular disorder. Indeed, reduced brain NO availability causes increased ß-amyloid deposition by several mechanisms, including hypoperfusion.
Purpose: To investigate the relationship between cerebral blood flow in the hippocampal and...
Conference Abstract
5.4 HIGH PWV IS ASSOCIATED WITH NANO-SCALE CHANGES IN THE MEDIAL LAYER OF THE INTERNAL MAMMARY ARTERY
Riaz Akhtar, Zhuo Chang, Maria Lyck Hansen, Lars Melholt Rasmussen
Pages: 57 - 57
Background: Arterial stiffening occurs as part of the natural ageing process. Degradation of the extracellular matrix (ECM) in the medial layer is typically implicated in arterial stiffening. However, little is known about how localised changes in arteries in terms of both structure and mechanical properties...
Conference Abstract
P.022 COMPARISON OF COMPLIOR, SPHYGMOCOR AND ARTERIOGRAPH FOR ASSESSMENT OF AORTIC PULSE WAVE VELOCITY IN PATIENTS WITH ARTERIAL HYPERTENSION
M.W. Rajzer, M. Klocek, W. Wojciechowska, I. Palka, M. Brzozowska-Kiszka, K.L. Kawecka-Jaszcz
Pages: 57 - 58
Conference Abstract
5.5 AGE-DEPENDENT TELOMERE ATTRITION, SHORT TELOMERES AND ATHEROSCLEROSIS
Simon Toupance, Anna Kearney-Schwartz, Mohamed Temmar, Cécile Lakomy, Carlos Labat, Patrick Rossignol, Faiez Zannad, Patrick Lacolley, Abraham Aviv, Athanase Benetos
Pages: 57 - 58
Background: Short leukocyte telomere length (LTL) is associated with atherosclerosis. The prevailing view is this association exists since LTL is a biomarker of cumulative inflammation and oxidative stress during adult life. However recent studies show that LTL in adults is defined mainly by LTL at birth...
Review Article
Remote telemonitoring of cardiovascular patients: Benefits, barriers, new suggestions
Ashkan Hashemi, Sormeh Nourbakhsh, Pedram Tehrani, Alireza Karimi
Pages: 57 - 63
Remote telemonitoring systems have been designed as a response to the new needs of home care for patients with chronic diseases. It also has the potential to ensure appropriate monitoring and treatment of patients as well as reducing the healthcare costs. Telemonitoring has been shown to be able to significantly...
Research Article
Effects of a Personalized Physical Exercise Program in the Arterial Stiffness in Older Adults
Telmo Pereira, Fabiana Santos, Inês Cipriano
Pages: 57 - 64
Introduction: This study was aimed at evaluating the effect of a tailored exercise intervention programme in the Arterial Stiffness (AS) of old adults.
Methods: Non-randomized intervention study, enrolling 32 community dwelling old adults, aged over 65 years (mean age: 83.28 ± 8.29 years), with no prior...
Research Article
Quantification of arterial wall inhomogeneity size, distribution, and modulus contrast using FSI numerical pulse wave propagation
Danial Shahmirzadi, Elisa E. Konofagou
Pages: 57 - 65
Changes in aortic wall material properties, such as stiffness, have been shown to accompany onset and progression of various cardiovascular pathologies. Pulse Wave velocity (PWV) and propagation along the aortic wall have been shown to depend on the wall stiffness (i.e. stiffer the wall, higher the PWV),...
Conference Abstract
P.023 INCREASED CARDIOVASCULAR RISK IN FIRST-DEGREE RELATIVES (WITHOUT ABDOMINAL AORTIC ANEURYSM, AAA) TO AAA PATIENTS?
R. De Basso, A. Fagerlind, T. Sandgren, Å. Rydén Ahlgren, T. Länne
Pages: 58 - 58
Conference Abstract
4.7 PARAMETERS OF THE RESERVOIR-WAVE APPROACH AND MORTALITY IN DIALYSIS POPULATION
Mohsen Agharazii, Catherine Fortier, Marie-Pier Desjardins, Martin Schultz, James Sharman
Pages: 58 - 58
Background: A new model has been proposed to explain hemodynamic consequences of arterial stiffness, which integrates both wave propagation and aortic reservoir function. The aim of this study was to assess the association between parameters of reservoir-wave analysis and all-cause mortality in a population...
Conference Abstract
5.6 CARDIOVASCULAR CONSEQUENCES OF EXTREME PREMATURITY: A FOLLOW-UP FROM THE EPICURE STUDY
Carmel McEniery, Joanne Beckman, Ian Wilkinson, Neil Marlow, John Cockcroft
Pages: 58 - 58
Background: Long-term outcomes following extremely preterm (EP) birth are becoming increasingly relevant, given improved survival rates. We previously reported altered arterial haemodynamics in 11 year olds who were <25 weeks gestation. The same individuals have now been re-evaluated in young adulthood.
Methods:...
Conference Abstract
P.024 CARDIAC FUNCTION, LARGE ARTERIES PROPERTIES AND MORTALITY IN OLDER PATIENTS WITH ATHEROSCLEROSIS
L. Handl, J. Filipovsky, P. Mudra, O. Mayer, P. Roucka
Pages: 58 - 58
Conference Abstract
4.8 ARTERIAL STIFFNESS AND ITS RELATIONSHIP TO MORTALITY IN PATIENTS WITH PERIPHERAL ARTERY DISEASE
Gabriel Dimitrov, Giovanni Scandale, Martino Recchia, Edoardo Perilli, Marzio Minola, Gianni Carzaniga, Maria Carotta, Mariella Catalano
Pages: 58 - 58
Background and aim: Several studies (1,2) suggest that patients with peripheral artery disease (PAD) show an increase in arterial stiffness, nevertheless the impact on mortality is less documented. (3)
Methods: 228 PAD patients mean age (68 ± 9 years) were followed-up for 4,8 ± 2 years. Anthropometric...
Conference Abstract
P.025 INCREASED ARTERIAL STIFFNESS AMONGST HEALTHY SOUTH ASIANS IN THE UNITED KINGDOM IN THE ABSENCE OF RAISED BLOOD PRESSURE
A. Gunarathne, J.V. Patel, R. Potluri, R. Butt, B. Gammon, C. Boos, N. Panja, E.A. Hughes, G.Y.H. Lip
Pages: 58 - 58
Conference Abstract
5.1 EFFECTS OF THE SGLT-2 INHIBITOR EMPAGLIFLOZIN ON VASCULAR FUNCTION AND CENTRAL HEMODYNAMICS IN PATIENTS WITH TYPE 2 DIABETES
Christian Ott, Kristina Striepe, Agnes Jumar, Marina Karg, Markus Schneider, Dennis Kannenkeril, Roland Schmieder
Pages: 58 - 58
Background: The selective sodium-glucose cotransporter 2 (SGLT-2) inhibitor empagliflozin leads to improved cardiovascular, renal and heart failure outcome in secondary prevention. To better understand these effects, we examined vascular function and central hemodynamics.
Methods: In this prospective,...
Conference Abstract
P.026 CLINICAL AND VASCULAR EFFECTS OF SWITCHING PATIENTS WITH CORONARY ARTERY DISEASE TO NEBIVOLOL
F. Ageev, I. Orlova, A. Sankova, E. Nuraliev, B. Kulev
Pages: 58 - 59
Review Article
The clinical importance of exercise blood pressure
Martin G. Schultz
Pages: 58 - 62
Clinical exercise stress testing is a common medical test performed in cardiology and exercise physiology clinics the world over. Measurement of blood pressure (BP) during testing is mandated. Whilst systolic BP should normally rise with incremental exercise, and diastolic BP remains relatively stable,...
Research Article
Assessment of peripheral vascular function with photoplethysmographic pulse amplitude
Tatiana Kuznetsova, Gregory Szczesny, Lutgarde Thijs, Dominique Jozeau, Jan D’hooge, Jan A. Staessen
Pages: 58 - 64
Background: Vasodilation of the peripheral arteries after reactive hyperaemia depends in part on the release of nitric oxide from endothelial cells. Previous studies mainly employed a fingertip tonometric device to derive pulse wave amplitude (PWA) and, therefore, measure PWA hyperaemic changes. Another...
Conference Abstract
P.027 ARTERIAL STIFFNESS IN RELATION TO URINARY ALDOSTERONE EXCRETION AND COLLAGEN METABOLISM IN ESSENTIAL HYPERTENSION
K. Stolarz-Skrzypek, W. Lubaszewski, A. Olszanecka, W. Wojciechowska, M. Cwynar, M. Loster, T. Grodzicki, K. Kawecka-Jaszcz
Pages: 59 - 59
Conference Abstract
5.2 REDUCED SUBLINGUAL ENDOTHELIAL GLYCOCALYX IN TYPE 1 DIABETICS WITH DIABETIC NEPHROPATHY
Signe Abitz Winther
Pages: 59 - 59
Background: Glycocalyx is a glycoprotein layer protecting the capillary endothelium. An impaired glycocalyx may precede the development of microvascular complications in diabetes. Capillaroscopy is a new method to estimate the dimensions of the glycocalyx by measuring the perfused boundary region (PBR)....
Conference Abstract
6.1 PERIPHERAL ARTERY DISEASE AND CENTRAL HEMODYNAMIC MODIFICATION
Mariella Catalano, Gabriel Dimitrov, Giovanni Scandale, Marzio Minola, Martino Recchia, Francesca Galli, Maria Carotta, Gianni Carzaniga
Pages: 59 - 59
Peripheral arterial disease (PAD) affects the hemodynamics of the lower limbs1 and is associated with increased cardiovascular risk and mortality2. The aim of this study was to evaluate central hemodynamics and to test the relationships between lower ankle-pressure index (ABI) and Augmentation index...
Conference Abstract
P.028 EPIGENETIC INTERACTION BETWEEN α-ADDUCIN AND RENIN-ANGIOTENSIN-SYSTEM GENES IN RELATION TO THE ELASTIC PROPERTIES OF THE FEMORAL ARTERY
J.S. Seidlerova, J.A.S. Staessen, T.N. Nawrot, HAS.-B. Struijker-Boudier, T.K. Kuznetsova, G.B. Bianchi, E.B. Brand, SMB.-H. Brand-Hermann, R.F. Fagard, J.F. Filipovsky
Pages: 59 - 59
Conference Abstract
5.3 HIGH FIT OLDER ADULTS MAINTAIN A SIMILAR ENDOTHELIAL RESPONSE TO ACUTE INFLAMMATION AS YOUNGER ADULTS
Elizabeth Schroeder, Abbi Lane-Cordova, Sushant Ranadive, Tracy Baynard, Bo Fernhall
Pages: 59 - 59
Inflammation is associated with an increased risk of cardiovascular events and reduced endothelial function. Higher cardiorespiratory fitness is associated with lower risk of cardiovascular events and improved vascular function. Whether fitness plays a role during acute inflammation is unknown.
Purpose:...
Conference Abstract
6.2 IMPACT OF DIABETES ON ARTERIAL STIFFNESS
Rogerio Toshiro Passos Okawa, Jorge Juarez Vieira Teixeira, Alex Cardoso Perez, Eigi Wilton de Souza, Giovanna Chiqueto Duarte, Guilherme Norio Hayakawa, Lorena Lima Gargaro, Marina Franciscon Gomes da Cruz, Michel Lima Moro Alves, Milene Cripa Pizatto de Araujo, Patrick Sadao Nishikawa, Rafaela Pelisson Regla, Rafael Campos do Nascimento
Pages: 59 - 59
Objectives/Background: The purpose of our study was to examine the impact of diabetes on arterial stiffness.
A systematic review, published by Cecelja and Chowienczyk (1), describes that pulse wave velocity (PWV), is highly predictive of cardiovascular events, and PWV is associated with age and blood-pressure,...
Conference Abstract
P.029 MECHANICAL CHARACTERISTICS OF CAROTID ARTERY WALLS IN RELATION WITH PREVALENT CARDIOVASCULAR DISEASES
I.M. Graf, F. Schreuder, W. Mess, A.P.G. Hoeks
Pages: 59 - 59
Conference Abstract
5.4 EFFECT OF ACUTE RESISTANCE EXERCISE ON ARTERIAL HEMODYNAMICS AND CEREBRAL BLOOD FLOW DYNAMICS: DOES SEX MATTER?
Alexander Rosenberg, Tommy Wee, Elizabeth Schroeder, Kanokwan Bunsawat, Georgios Grigoriadis, Garett Griffith, Bo Fernhall, Tracy Baynard
Pages: 59 - 60
High-intensity resistance exercise (RE) acutely increases arterial stiffness and blood pressure (BP), coupled with reduced cerebral blood flow velocity (CBFv) and greater flow pulsatility in the cerebral circulation, which may be detrimental to cerebral microvasculature. Because females have different...
Conference Abstract
6.3 ARTERIAL STIFFNESS IS ASSOCIATED WITH LOW-DENSITY NON-CALCIFIED CORONARY PLAQUES IN PATIENTS WITH TYPE 2 DIABETES AND HEALTHY CONTROLS
Kristian L. Funck, Esben Laugesen, Kristian Oevrehus, Jesper M. Jensen, Bjarne L. Noergaard, Damini Dey, Troels K. Hansen, Per L. Poulsen
Pages: 59 - 60
Background: Arterial stiffness may provide non-invasive information about cardiovascular risk in patients with type 2 diabetes. We investigated the association between arterial stiffness and subclinical coronary atherosclerosis in patients with type 2 diabetes and healthy controls.
Methods: Patients...
Conference Abstract
P.030 ARTERIAL STIFFNESS IS PREDICTOR CARDIOVASCULAR EVENTS IN MEN WITH CORONARY ARTERY DISEASE
I. Orlova, F. Ageev, E. Nuraliev
Pages: 59 - 60
Short Communication
Combined imaging, computational and histological analysis of a ruptured carotid plaque: A patient-specific analysis
Giulia Soloperto, Niall G. Keenan, Mary N. Sheppard, Jacques Ohayon, Nigel B. Wood, Dudley J. Pennell, Raad H. Mohiaddin, Xiao Yun Xu
Pages: 59 - 65
Background: Rupture of carotid plaques is an important cause of cerebrovascular events. Several factors, including wall shear stress (WSS), plaque morphology and peak cap stress, have been associated with plaque vulnerability. The aim of this study was to investigate the relationship between these factors...
Mini Review
Inflammation and large arteries: Potential mechanisms for inflammation-induced arterial stiffness
Kaisa M. Mäki-Petäjä, Ian B. Wilkinson
Pages: 59 - 64
Systemic inflammatory conditions are associated with an increased risk of cardiovascular disease (CVD). How exactly inflammation leads to this is not fully understood, but it has been suggested that arterial stiffening, could provide potential mechanisms to explain it. Chronic, systemic inflammatory...
Research Article
Covid-19 Effects on ARTErial StIffness and Vascular AgeiNg: CARTESIAN Study Rationale and Protocol
Rosa Maria Bruno, Bart Spronck, Bernhard Hametner, Alun Hughes, Patrick Lacolley, Christopher C. Mayer, Maria Lorenza Muiesan, Chakravarthi Rajkumar, Dimitrios Terentes-Printzios, Thomas Weber, Tine Willum Hansen, Pierre Boutouyrie, on behalf of the ARTERY Society
Pages: 59 - 68
In December 2019, an outbreak of pneumonia caused by a novel Coronavirus (COVID-19) spread rapidly worldwide. Although the clinical manifestations of COVID-19 are dominated by respiratory symptoms, the cardiovascular system is extensively affected at multiple levels. Due to the unprecedented consequences...
Conference Abstract
P.031 CHRONIC COFFEE CONSUMPTION HAS A LESS POTENT EFFECT ON AORTIC STIFFNESS THAN CAFFEINE
N. Ioakeimidis, C. Vlachopoulos, N. Alexopoulos, I. Dima, P. Xaplanteris, A. Gravos, K. Baou, C. Stefanadis
Pages: 60 - 60
Conference Abstract
5.5 IMPACT OF PULMONARY ENDARTERECTOMY ON PULMONARY ARTERIAL WAVE PROPAGATION AND RESERVOIR FUNCTION
Junjing Su, Alun Hughes, Ulf Simonsen, Jens Erik Nielsen-Kudsk, Kim Parker, Luke Howard, Søren Mellemkjaer
Pages: 60 - 61
Background: Recent studies have demonstrated distinctive arterial wave characteristics in patients with chronic thromboembolic pulmonary hypertension (CTEPH)1. Therefore, we aimed to assess the impact of pulmonary endarterectomy (PEA) on pulmonary arterial wave propagation and reservoir function in CTEPH...
Conference Abstract
6.4 LARGE AND SMALL ARTERY CROSSTALK IN PATIENTS WITH TYPE 2 DIABETES
Jonathan Mathias Baier, Esben Laugesen, Søren Tang Knudsen, Per Løgstrup Poulsen, Toke Bek
Pages: 60 - 60
Background: Vascular complications to diabetes mellitus have, traditionally, been divided in to micro- and macroangiopathy. However, a growing body of evidence has put this categorical division into question, as large artery stiffness has been associated with microvascular complications in diabetics,...
Conference Abstract
P.032 GRADED ASSOCIATION BETWEEN LARGE ARTERY STIFFNESS AND ERECTILE DYSFUNCTION SEVERITY AND DURATION IN ESSENTIAL HYPERTENSIVE MEN
N. Ioakeimidis, C. Vlachopoulos, A. Samentzas, A. Tsokanis, G. Antoniou, K. Rokkas, A. Askitis, C. Stefanadis
Pages: 60 - 60
Conference Abstract
6.5 ASSOCIATION BETWEEN INCREASED ARTERIAL STIFFNESS AND HBA1C AND LDL CHOLESTEROL LEVEL IN TYPE 2 DIABETES PATIENTS
Ilona Hegyi, Terez Szabo, Eszter Szele, Istvan Vasas
Pages: 60 - 60
Background: In patient with type 2 diabetes mellitus (T2DM) the atherosclerosis apper in younger age, in both gender and the cardiovascular risk is much higher. The aim of our study was to examine the association between pulse wave velocity (PWV) and glycated haemoglobin (HbA1c) and low density lipoprotein...
Conference Abstract
P.033 ASSOCIATION BETWEEN ARTERIAL WAVE REFLECTIONS AND PENILE DOPPLER FINDINGS IN HYPERTENSIVE MEN WITH VASCULOGENIC ERECTILE DYSFUNCTION
C. Vlachopoulos, N. Ioakeimidis, K. Rokkas, K. Aznaouridis, A. Tsokanis, A. Samentzas, C. Fassoulakis, C. Stefanadis
Pages: 60 - 60
Conference Abstract
6.6 AORTIC-BRACHIAL STIFFNESS MISMATCH IN PATIENTS WITH ARTERIAL HYPERTENSION AND TYPE 2 DIABETES MELLITUS
Ekaterina Starostina, Elena Troitskaya, Yulia Kotovskaya, Zhanna Kobalava
Pages: 60 - 61
Background: Patients with type 2 diabetes have a high risk of CVD. Arterial stiffness gradient is a new prognostic predictor of mortality previously assessed only in dialysis population1–2.
The aim of the study was to assess arterial stiffness and stiffness gradient in diabetic patients with arterial...
Conference Abstract
P.034 THE INFLUENCE OF GENDER, CYCLOOXYGENASE-2 INHIBITION, AND HYPERGLYCEMIA ON VASCULAR FUNCTION IN UNCOMPLICATED TYPE 1 DIABETES MELLITUS
D.Z.I. Cherney, J.A. Miller, J.W. Scholey, M.G. Dekker, E.B. Sochett, C. Slorach, T.J. Bradley
Pages: 60 - 61
Research Article
Gender as a moderator in the relationship between anxiety and carotid intima-media thickness: The PREVENCION study
Diana A. Chirinos, Belissa Salinas-Najarro, Roberto Paz-Manrique, Zubair Khan, Waheed Raja, Francisco Ibañez, Fernando Corrales-Medina, Humberto Zea-Diaz, Julio A. Chirinos, Josefina Medina-Lezama
Pages: 60 - 66
Background: Previous studies regarding the association of atherosclerotic risk and anxiety have yielded conflicting results. Carotid intima–media thickness (cIMT) is an early marker of subclinical atherosclerosis and an independent predictor of cardiovascular risk. We aimed to determine the relationship...
Research Article
The effects of central arterial pressure and autonomic dysfunction on elevations in N-terminal pro-B-type natriuretic peptide (NT-proBNP) in men with diabetes
S. Bunce, A. Stride, C. Matthews, S. Shaw, J.C. Smith
Pages: 60 - 66
Background: In diabetes, left ventricular dysfunction independent of coronary disease is common and is associated with elevations in NT-proBNP. Our aims were to determine the relative importance of central aortic pressure, cardiovascular autonomic function and arterial stiffness as predictors of elevated...
Conference Abstract
P.035 BIOLOGICAL VARIABILITY OF THE ULTRASONOGRAPHIC ASSESSMENT OF ENDOTHELIAL DYSFUNCTION IN CHILDREN WITH HIGH RISK OF MANIFESTATION OF ATHEROSCLEROSIS☆,☆☆
P. Jehlicka, F. Stozický, J. Varvarovská, J. Racek, O. Mayer, J. Filipovský, L. Trefil
Pages: 61 - 61
Conference Abstract
5.6 LONGITUDINAL FOLLOW-UP OF ARTERIAL STIFFNESS IN PATIENTS WITH SEVERE PSORIASIS TREATED BY ANTI-IL12/IL-23 COMPARED TO ANTI-TNF ALPHA
Hakim Khettab, Manuelle Viguier, Idir Hamdidouche, Hervé Bachelez, Pierre Boutouyrie
Pages: 61 - 61
Patients with chronic severe psoriasis are at increased cardiovascular risk (CVR). Modern systemic treatments of psoriasis involve anti-TNF alpha (ATNF) and more recently introduced anti-IL12/IL-23 (ustekinumab, AIL12/23) which, by interfering with IL-17, a possibly vasculoprotective cytokine, may increase...
Conference Abstract
6.7 FIRST EVIDENCE OF PULSATILE PRESSURE INTERACTION BETWEEN THE MACRO-VASCULATURE AND MICRO-VASCULATURE: PROOF-OF-CONCEPT BY ASSOCIATION WITH KIDNEY DYSFUNCTION AMONG PATIENTS WITH TYPE 2 DIABETES
Rachel Climie, Dean Picone, Sarah Blackwood, Ahmad Qasem, Stephen Rattigan, James Sharman
Pages: 61 - 61
Objectives: It is widely thought that excess pulsatile pressure energy from increased stiffness of large central arteries (macro-vasculature) is transmitted to capillary networks (micro-vasculature) and causes end-organ damage (i.e. kidneys). However, this hypothesis has never been tested, and we sought...
Conference Abstract
P.036 ASYMMETRIC DIMETHYLARGININE AND OXIDIZED LDL – SENSITIVE BIOCHEMICAL MARKERS OF ENDOTHELIAL DYSFUNCTION IN CHILDREN WITH FAMILIAR HYPERCHOLESTEROLEMIA☆
P. Jehlicka, F. Stozický, J. Racek, O. Mayer, L. Trefil, J. Filipovský
Pages: 61 - 61
Conference Abstract
5.7 SUBPOPULATIONS OF CIRCULATING T LYMPHOCYTES IN OBESE PATIENTS UNDERGOING BARIATRIC SURGERY
C. Agabiti Rosei, C. Rossini, F. Mittempergher, A. Titi, N. Portolani, C. De Ciuceis, S. Caletti, M.A. Coschignano, V. Trapletti, E. Porteri, P. Pileri, E. Agabiti Rosei, D. Rizzoni
Pages: 61 - 61
Objective: It has been previously demonstrated that T lymphocytes may be involved in the development of hypertension and microvascular remodeling, and that circulating T effector lymphocytes may be increased in hypertension. In particular, Th1 and Th17 lymphocytes may contribute to the progression of...
Conference Abstract
6.8 THE RELATIONSHIP BETWEEN DIASTOLIC FUNCTION AND CENTRAL HEMODYNAMICS IN DIABETIC HYPERTENSIVE PATIENTS
Davide Agnoletti, Filippo Valbusa, Ari Lieber, Guido Arcaro, Michel Safar, Jacques Blacher
Pages: 61 - 61
Background: Diabetic hypertensives patients present different hemodynamic pattern than only hypertensive patients. We aimed to investigate the relationship between the diastolic function and the pulse pressure amplification (PPA), an index combining both arterial stiffness and wave reflexion, in diabetic...
Conference Abstract
P.037 PRESSURE WAVEFORM ESTIMATION IN THE COMMON CAROTID ARTERY – DIFFERENT METHODS IN COMPARISON
I. Zaccari, A.C. Rossi, E.M.H. Bosboom, P.J. Brands
Pages: 61 - 61
Conference Abstract
6.9 ANTIPLATELET AND VASCULAR EFFECTS OF ASPIRIN IN HEALTHY PERSONS AND PATIENTS WITH TYPE 2 DIABETES
Liv Vernstroem Hald, Anne-Mette Hvas, Erik Lerkevang Grove, Esben Laugesen, Kristian Loekke Funck, Per Loegstrup Poulsen
Pages: 61 - 61
Background: Treatment with aspirin is a cornerstone in the secondary prevention of cardiovascular disease (CVD) in diabetes, whereas its place in primary prevention remains controversial.
The effect of once-daily aspirin on platelet aggregation is unclear in patients with diabetes. Furthermore, the...
Conference Abstract
P.038 INTERRELATION BETWEEN DYNAMICS OF CHANGES ENDOTHELIUM-DEPENDENT DILATATION AND LOCAL RIGIDITY OF THE BRACHIAL ARTERY IN PATIENTS WITH HYPERLIPIDEAMIA ON A BACKGROUND OF RECEPTION STATINS WITHIN 6 MONTHS
B.D. Koulev, N.V. Sankova, Nuraliev E. Yu, F.T. Ageev
Pages: 61 - 61
Conference Abstract
6.10 PERIPHERAL SENSORY NEUROPATHY AND VASCULAR ANGIOGENIC FACTORS IN TYPE 2 DIABETES PATIENTS IN GHANA
Kwame Yeboah, Daniel A. Antwi, Ben Gyan
Pages: 61 - 62
Background: Impaired angiogenesis may be amongst the possible mechanism underlining the development of peripheral sensory neuropathy (PSN) in type 2 diabetes (T2DM) patients.(1) Angiogenesis is regulated by circulating vascular growth factor, notably, angiopoietin (Ang)-1, Ang-2 and vascular endothelial...
Conference Abstract
P.039 THE NUMBER OF CD34+ CELLS IN PATIENTS WITH STABLE ANGINA PECTORIS: INFLUENCE OF ABNORMAL GLUCOSE METABOLISM AND CORONARY ANGIOPLASTY
M. Ruda, O. Vyborov, T. Arefieva, Yu. Karpov, Ye. Parfyonova
Pages: 61 - 62
Conference Abstract
P.040 ASSOCIATION OF ARTERIAL STIFFNESS, CAROTID INTIMA-MEDIA THICKNESS, CAROTID PLAQUES AND FLOW-MEDIATED DILATATION WITH METABOLIC SYNDROME
M. Kovaite, Z. Petrulioniene, L. Ryliskyte, J. Badariene, A. Cypiene, A. Laucevicius
Pages: 62 - 62
Conference Abstract
PERIPHERAL BLOOD FLOW REGULATION IN RESPONSE TO SYMPATHETIC STIMULATION IN INDIVIDUALS WITH DOWN SYNDROME
Thessa I.M. Hilgenkamp, Sang Ouk Wee, Tracy Baynard, Bo Fernhall
Pages: 62 - 62
Background: Individuals with Down syndrome (DS) experience autonomic dysfunction, with reduced sympathetic and parasympathetic control. This results in alterations in resting heart rate and blood pressure and attenuated responses to sympathoexcitatory stimuli. It is unknown to what extent this impacts...
Conference Abstract
P2 LOCAL ABDOMINAL VERSUS THORACIC AORTA STIFFENING IN HYPERTENSIVE RATS UNDER EITHER NO RESTRICTION OR SALTED DIET
George Lindesay, Neila Malti, Christophe Ragonnet, Marc Isabelle, Nicole Villeneuve, Yvonnick Bézie, Christine Vayssettes-Courchay
Pages: 62 - 62
Background: Hypertensive humans exhibit reduced nitric oxide bioavailability and increased salt sensitivity, both of which are related to central artery stiffening. We studied the effect of 5 week NO restriction via L-NAME treatment in spontaneously hypertensive rats (SHR) and 5% salted diet in salt-sensitive...
Conference Abstract
7.1 THE DETRIMENTAL EFFECTS OF LIVE FIREFIGHTING ON ARTERIAL FUNCTION IN FIREFIGHTERS
Alexander Rosenberg, Kanokwan Bunsawat, Tommy Wee, Tracy Baynard, Gavin Horn, Denise Smith, Bo Fernhall
Pages: 62 - 62
Background: Aging is associated with increased arterial stiffness and wave reflection, which is predictive of all-cause cardiovascular (CV) mortality (1–3). Firefighters have the highest cardiovascular mortality of any occupational group (4). High levels of heat stress, physical exertion, and elevated...
Conference Abstract
P.041 ARTERIAL STIFFNESS MAY BE DETERMINED BY ASYMMETRIC DIMETHYLARGININE (ADMA)
S. Hickson, Y. Ben-Shlomo, C. McEniery, M. Spratt, M. Munnery, M. Ashby, I. Wilkinson, J. Cockcroft
Pages: 62 - 62
Conference Abstract
P3 THE EXTENT OF ENDOTHELIAL DYSFUNCTION IN THE FEMORAL ARTERY IS SIMILAR IN THE JUVENILE MALE AND FEMALE SPONTANEOUSLY HYPERTENSIVE RATS
Peter Balis, Iveta Bernatova, Angelika Puzserova
Pages: 62 - 62
Objectives: Endothelial dysfunction (ED) plays an important role in the pathogenesis of hypertension. In this work, we studied sex differences in the endothelium-dependent relaxation (EDR) of the femoral artery (FA) and its nitric oxide (NO)-dependent and NO-independent components in peri-pubertal (7-week-old)...
Conference Abstract
7.2 POOR SLEEP QUALITY RELATED TO WORSE VASCULAR FUNCTION IN INDIVIDUALS WITH MULTIPLE SCLEROSIS
Thessa Hilgenkamp, Garett Griffith, Robert Motl, Tracy Baynard, Bo Fernhall
Pages: 62 - 62
Background: Poor sleep quality has been related to poor vascular function and higher risk of cardiovascular disease in the general population. Persons with multiple sclerosis (MS) exhibit a high cardiovascular risk, and report poor sleep quality. To date, the association between sleep quality and vascular...
Conference Abstract
VALIDATION OF ULTRASOUND DETERMINATION OF LOCAL PULSE WAVE VELOCITY IN THE HUMAN ASCENDING AORTA AGAINST MRI MEASUREMENTS
Negoita Madalina, Manisty Charlotte, Bhuva Anish, Hughes Alun, Parker Kim, Khir Ashraf
Pages: 62 - 62
Background: Pulse Wave Velocity (PWV) is a measure of arterial stiffness which predicts cardiovascular risk independently of blood pressure. Local PWV can be measured non-invasively in the ascending aorta of adults by means of Ultrasound (US), using successive recordings of Diameter (D) and the velocity...
Conference Abstract
P.042 NOT ONLY DIABETES MELLITUS, BUT ALSO IMPAIRED GLUCOSE TOLERANCE IS ASSOCIATED WITH ERECTILE DYSFUNCTION IN HYPERTENSIVE PATIENTS
N. Alexopoulos, C. Vlachopoulos, G. Vyssoulis, P. Pietri, K. Aznaouridis, N. Ioakeimidis, C. Stefanadis
Pages: 62 - 62
Conference Abstract
P4 SOCIAL STRESS-INDUCED BLOOD PRESSURE INCREASE IN BORDERLINE HYPERTENSIVE RATS IS ASSOCIATED WITH ENDOTHELIAL DYSFUNCTION IN THE RESISTANT ARTERIES
Angelika Puzserova, Ruzena Sotnikova, Jozef Torok, Anna Zemancikova, Iveta Bernatova
Pages: 62 - 63
Objectives: Several studies have observed that altered endothelial function is involved in the development of stress-induced hypertension. The aim of this study was to investigate the effects of chronic social stress (crowding) on endothelium-dependent relaxation (EDR) of the superior mesenteric artery...
Conference Abstract
P.043 INFLUENCE OF CATECHOLAMINES ON ARTERIAL STIFFNESS IN PHEOCHROMOCYTOMA
O.P. Petrák, B.S. Štrauch, T.Z. Zelinka, R.H. Holaj, J.R. Rosa, T.P. Pikus, A.V. Vránková, M.K. Kasalický, L.S. Šafa’ík, J.W. Widimský
Pages: 62 - 63
Conference Abstract
P.044 EFFECT OF MILD INCREASE OF PHYSICAL ACTIVITY ON MICROVASCULARY REACTIVITY IN OBESE SUBJECTS WITH DIABETES MELLITUS TYPE 2
M.K. Krcma, D.C. Cechurova, Z.R. Rusavy
Pages: 63 - 63
Conference Abstract
THE REGULATORY ROLE OF COAGULATION FACTORS ON ARTERIAL FUNCTION
Jeremy Lagrange
Pages: 63 - 63
The coagulation takes place in the physiological system of hemostasis. Hemostasis is known to be disturbed in many diseases leading to hemorrhages or thrombosis. Despite the role of coagulation in hemostasis, recent evidence suggest that coagulation factors are involved in other physiological as well...
Conference Abstract
P5 ERYTHROCYTE DEFORMABILITY AND NITRIC OXIDE PRODUCTION IN ANIMAL MODEL OF PRIMARY HYPERTENSION AND THEIR AGE-DEPENDENT CHANGES
Jana Radosinska, Peter Balis, Angelika Puzserova
Pages: 63 - 63
Objectives: Reduced deformability of red blood cells (RBC) plays an important role in etiology of various diseases including cardiovascular. The nitric oxide (NO) was identified as one of factors responsible for maintenance of RBC deformability. Reduced bioavailability of NO might be important in the...
Conference Abstract
7.3 ASSESSMENT OF BLOOD PRESSURE AND HEART RATE VARIABILITY IN MULTIPLE SCLEROSIS
Fatemeh Shirbani, Edward Barin, Mark Butlin, Alberto Avolio
Pages: 63 - 63
Background: Reported cardiovascular autonomic dysfunction (CAD) prevalence in Multiple Sclerosis (MS) varies between studies. As CAD lowers quality of life and may contribute to sudden death in MS, early CAD detection may assist treatment and risk identification.
Methods: In 23 MS patients and age and...
Conference Abstract
P.045 REVERSIBLE LEFT VENTRICULAR DYSFUNCTION AND BRAIN NATRIURETIC PEPTIDE (BNP) PLASMA LEVELS IN PATIENTS WITH TRAUMATIC BRAIN INJURY
J. Papanikolaou, J. Poularas, A. Kalogeromitros, D. Karakitsos, E. Matsakas, A. Karabinis
Pages: 63 - 63
Conference Abstract
NEW DRUG TARGETS FOR SLOWING VASCULAR AGEING: SIRT1, SIRT5, JUND AND P66SCH
Luca Liberale
Pages: 63 - 63
Western societies are aging due to an increasing life span, decreased birth rates, and improving social and health conditions. On the other hand, the prevalence of cardiovascular (CV) and cerebrovascular (CBV) diseases rises with age. Thus, in view of the ongoing aging pandemic, it is appropriate to...
Conference Abstract
P6 ANGIOTENSIN AT2 RECEPTOR AGONIST, COMPOUND 21, MAINTAINS VASCULAR INTEGRITY AND PREVENTS ABDOMINAL AORTIC ANEURYSM PROGRESSION IN THE RAT
Christoph Lange, Manuela Sommerfeld, Pawel Namsolleck, Ulrich Kintscher, Thomas Unger, Elena Kaschina
Pages: 63 - 63
The effects of the selective angiotensin AT2 receptor agonist, compound 21 (C21), on abdominal aortic aneurysm (AAA) formation were investigated in normotensive Wistar rats.
AAA was induced by perfusion of isolated aortic segments with elastase (Anidjar/Dobrin model). Treatment with C21 (0.03 and 0.3...
Conference Abstract
7.4 HIGHER CAROTID STRAIN IN INDIVIDUALS WITH DOWN SYNDROME AT REST AND DURING HYPOVOLEMIC SYMPATHOEXCITATION
Sang Ouk Wee, Alexander Rosenberg, Bunsawat Kanokwan, Garett Griffith, Tracy Baynard, Bo Fernhall
Pages: 63 - 63
Background: Arterial stiffness and large artery function are independent risk factors for cardiovascular disease.(1) Individuals with Down Syndrome (DS) have autonomic dysfunction and known to have lower incidence of cardiovascular disease.(2) Limited literatures showed no difference in arterial stiffness...
Conference Abstract
P.046 IMPAIRED ARTERIAL ELASTIC PROPERTIES IN HUMAN IMMUNODEFICIENCY VIRUS INFECTED NAïVE PATIENTS. THE ROLE OF SUBCLINICAL INFLAMMATION
G. Antoniou, C. Vlachopoulos, D. Tsiachris, H. Sambatakou, K. Baou, N. Alexopoulos, A. Archimandritis, C. Stefanadis
Pages: 63 - 63
Conference Abstract
GREATER AORTIC STIFFNESS IS ASSOCIATED WITH LOWER HIPPOCAMPAL CEREBROVASCULAR RESERVE BUT NOT CEREBRAL BLOOD FLOW OR AMYLOID IN MIDDLE-AGED AND OLDER ADULTS
Lyndsey E. DuBose, Laura L. Boles Ponto, David J. Moser, Gary L. Pierce
Pages: 63 - 63
Background: Recent studies suggests cerebrovascular dysfunction precedes amyloid deposition and cognitive impairment in Alzheimer’s disease (AD). However, if functional impairments in the hippocampus, as evidenced by reduced hippocampal cerebral blood flow (CBF) during memory stimulation and cerebrovascular...
Conference Abstract
P7 THE URINARY PEPTIDOMIC SIGNATURE OF AORTIC STIFFNESS REVEALS MOLECULAR PATHWAYS AND DRUG TARGETS
Zhen-Yu Zhang, Makis Izoidakis, Wen-Yi Yang, Lutgarde Thijs, Fang-Fei Wei, Qi-Fang Huang, Joost Schanstra, Jens-Uwe Voigt, Tatiana Kuznetsova, Peter Verhamme, Antonia Vlahou, Harald Mischak, Jan Staessen
Pages: 63 - 63
Background: Molecular pathways leading to stiffening of the central arteries are poorly understood. We searched for differentially expressed proteins by urinary peptidomic analysis in patients with arterial stiffness and healthy controls in a case–control study.
Methods: To identify urinary peptides...
Conference Abstract
7.5 RETINAL VESSEL RESPONSES TO FLICKERING LIGHT PROVOCATION IN A COHORT OF BLACK AND WHITE TEACHERS: THE SABPA STUDY
Wayne Smith, Walthard Vilser, Konstantin Kotliar
Pages: 63 - 63
Background: Retinal microvascular function can be assessed using flicker light induced provocation (FLIP). Reduced vessel dilation responses to FLIP are noted in various disease conditions. Comparative studies between ethnic groups are scarce, while the importance of different phases of the vessel responses...
Conference Abstract
P.047 EXAMINATION OF PRESSURE AND VOLUME PULSE WAVES
C.C. Winchester, N.Y. Chou, L.W. Winchester
Pages: 63 - 64
Conference Abstract
P8 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 LEVELS AND ARTERIAL FUNCTION
Losif Koutagiar, Charalambos Vlachopoulos, Dimitrios Terentes-Printzios, John Skoumas, Nikitas Skliros, Magkas Nikolaos, Antigoni Miliou, Dimitrios Tousoulis
Pages: 63 - 64
Purpose/Background/Objectives: Proprotein convertase subtilisin/kexin type 9 (PCSK9) levels are modestly but significantly associated with increased risk of total cardiovascular events. Aortic stiffness and wave reflections are also important predictors of cardiovascular events. The aim of this pilot...
Conference Abstract
7.6 THE DIFFERENCE IN GLUTATHIONE PEROXIDASE ACTIVITY ON ARTERIES OF A BI-ETHNIC POPULATION: THE SABPA STUDY
Johannes van Rooyen, Zurietta Schoeman, Carina Mels
Pages: 63 - 63
Background and objectives: From the literature it is evident that increased oxidative stress is integral in the development of cardiovascular disease. We therefore aimed to compare glutathione peroxidase (GPx) and glutathione reductase (GR) activity between black and white Africans, and to investigate...
Research Article
Resistance training-induced decreases in central arterial compliance is associated with increases in serum thromboxane B2 concentrations in young men
Kaname Tagawa, Song-Gyu Ra, Hiroshi Kumagai, Yuriko Sawano, Kosaku Yamamoto, Toru Yoshikawa, Youngju Choi, Yasuko Yoshida, Kazuhiro Takekoshi, Seiji Maeda
Pages: 63 - 70
Background: Reduction in central arterial compliance is an independent risk factor for cardiovascular disease, and is caused by high-intensity resistance training. The thromboxane has both potent vasoconstrictive and platelet aggregation effects, and is associated with cardiovascular diseases. However,...
Review Article
Stiff vessels approached in a flexible way: Advancing quantification and interpretation of arterial stiffness☆
Bart Spronck
Pages: 63 - 68
Introduction: Although pulse wave velocity (PWV), a proxy of arterial stiffness, is a strong predictor of cardiovascular complications, it is confounded by blood pressure (BP) and heart rate at the time of examination. Furthermore, establishing whether an artery behaves stiffer or less stiff does not...
Conference Abstract
P.048 IDENTIFYING ASSOCIATIONS OF REDUCED ADIPOSITY AND IMPROVED EARLY MARKERS OF ATHEROSCLEROSIS FROM A LIFESTYLE INTERVENTION AIMED AT OVERWEIGHT ADOLESCENTS
T.J. Bradley, J.G. Wengle, C. Slorach, J. Hamilton, C. Manlhiot, R. Sananes, K. Adeli, D.K. Katzman, C.S. Birken, B.W. McCrindle
Pages: 64 - 64
Conference Abstract
ASSOCIATION OF PULSE WAVE VELOCITY AND BODY MASS INDEX IN HEALTHY MEXICAN POPULATION
Daniela Avila Novoa, M. Cárdenas, E.G. Cardona, D. Cardona, F. Grover, C. Ramos, J. Trujillo
Pages: 64 - 64
Rational: Cardiovascular diseases represent the main cause of morbidity and mortality throughout the world (1). Arterial stiffness has shown to be an important predictor of cardiovascular events, and pulse wave velocity (PWV) is a marker of subclinical organ damage which can be measured by different...
Conference Abstract
P9 THE PARTICIPATION OF NITRIC OXIDE AND HYDROGEN SULPHIDE SIGNALISATION IN VASOACTIVE RESPONSES OF RAT THORACIC AORTA IN CONDITION OF DEVELOPED SPONTANEOUS HYPERTENSION
Andrea Berenyiova, Angelika Puzserova, Marian Grman, Frantisek Kristek, Sona Cacanyiova
Pages: 64 - 64
Our previous study in young spontaneously hypertensive rats (SHR) confirmed a participation of nitric oxide (NO) and hydrogen sulphide (H2S) in probably inherent adaptive strategy of conduit arteries in condition of sustained hypertension. The aim of study was to confirm or refuse the compensatory mechanisms...
Conference Abstract
7.7 THE EFFECT OF MARINE N-3 POLYUNSATURATED FATTY ACIDS ON CARDIAC AUTONOMIC AND HEMODYNAMIC FUNCTION IN PATIENTS WITH PSORIATIC ARTHRITIS: A RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL
Salome Kristensen, Erik Berg Schmiddt, Annette Schlemmer, Claus Rasmussen, Esther Lindgreen, Martin Berg Johansen, Jeppe Hagstrup Christensen
Pages: 64 - 64
Background: Patients with psoriatic arthritis are at high cardiovascular risk. Marine n-3 polyunsaturated fatty acids (PUFA) may reduce the incidence of cardiovascular disease. The aim of this study was to investigate the effect of marine n-3 PUFA on cardiac autonomic function and vascular function in...
Conference Abstract
P.049 THE P22PHOX -930A/G POLYMORPHISM OF NADPH OXIDASE: AN INDEPENDENT GENETIC DETERMINANT OF WAVE REFLECTIONS
P. Xaplanteris, C. Vlachopoulos, K. Baou, C. Vasiliadou, I. Dima, N. Ioakeimidis, D. Kardara, C. Stefanadis
Pages: 64 - 64
Conference Abstract
WHICH IS MORE CORRELATED WITH HYPERTENSIVE ORGAN DAMAGE, SLEEP BLOOD PRESSURE ASSESSED BY SELF-MEASURED AT HOME OR AMBULATORY BLOOD PRESSURE MONITORING?: THE JAPAN MORNING SURGE-HOME BLOOD PRESSURE (J-HOP) STUDY
Sirisawat Wanthong, Tomoyuki Kabutoya, Satoshi Hoshide, Kazuomi Kario
Pages: 64 - 64
Objective: To assess the associations with hypertensive target organ damage (TOD) of sleep SBP assessed by self-measured home blood pressure monitoring (HBPM) and ambulatory blood pressure monitoring (ABPM).
Methods: Data of 1008 participants in the J-HOP study who measured sleep BP using both HBPM,...
Conference Abstract
P10 LOSS OF ENDOTHELIUM-DEPENDENT REGULATION OF ARTERIAL WALL VISCOSITY IN ESSENTIAL HYPERTENSION
Frederic Roca, Jeremy Bellien, Michele Lacob, Robinson Joannides
Pages: 64 - 64
Background: Nitric oxide (NO) and epoxyeicosatrienoic acids (EETs) regulate arterial wall viscosity (AWV) in young subjects (1). During hypertension, characterised by a decrease in endothelium-derived NO and an early disappearance of EETs, AWV is not modified (2,3). We compared the role of NO and EETs...
Conference Abstract
7.8 ARTERIAL STIFFNESS AND SYSTEMIC INFLAMMATION IN COPD PATIENTS
Renata Marietta Bocskei, Lilla Tamasi, Bela Benczur, Attila Cziraki, Gyorgy Losonczy, Aniko Bohacs
Pages: 64 - 64
Background: COPD is one of the leading causes of mortality worldwide. Systemic low-grade inflammation is a common finding in COPD. Soluble urokinase-type plasminogen activator receptor (suPAR) indicates an inflammatory state and it has an association with atherosclerosis and cardiovascular disease (CVD)....
Conference Abstract
P.050 PREDICTIVE FACTORS FOR MACRO- AND MICRO-VASCULAR COMPLICATIONS IN TYPE 2 DIABETES
H. Rosolova, B. Petrlova, J. Filipovsky, P. Sifalda, J. Simon
Pages: 64 - 64
Conference Abstract
MOLECULAR AND CELLULAR CHANGES IN ARTERIAL FUNCTION OVER THE LIFE COURSE – FROM ACCELERATED AGEING TO CALCIFICATION
Catherine M. Shanahan
Pages: 64 - 64
Vascular stiffening and calcification are hallmarks of ageing and these pathologies are accelerated in patients with diabetes and renal failure. Emerging evidence has defined a role for nuclear lamina defects and the DNA damage response in driving vascular calcification. The mechanisms responsible are...
Conference Abstract
7.9 CAROTID ARTERY STIFFNESS IS ASSOCIATED WITH CT-MEASURED LUNG AIR-TRAPPING IN COPD PATIENTS AND CONTROLS INDEPENDENT OF AGE, BLOOD PRESSURE AND SMOKING HISTORY
Gary Pierce, John Newell, Alejandro Comellas, Eric Hoffman, Kelsey Warner, Anna Croghan, Lyndsey DuBose, Peg Nopoulos, Vince Magnotta, Stephan Arndt, Karin Hoth
Pages: 64 - 64
Background: Early stages of chronic obstructive pulmonary disease (COPD) are characterized by loss of the terminal bronchioles and ‘air trapping’ often before overt emphysema manifests (1). COPD patients are also at risk for cardiovascular disease (CVD), therefore, we hypothesized that the degree of...
Conference Abstract
P.051 ARTERIAL STIFFNESS IS INCREASED IN PATIENTS WITH HEPATITIS C VIRUS SEROPOSITIVITY, BUT NOT IN PATIENTS WITH HEPATITIS B VIRUS SEROPOSITIVITY AND THE ROLE OF LEPTIN
K. Baou, C. Vlachopoulos, E. Manesis, N. Ioakeimidis, J. Koskinas, P. Xaplanteris, I. Dima, A. Archimadritis, C. Stafanadis
Pages: 64 - 65
Conference Abstract
NOVEL RESEARCH FUNDING OPPORTUNITIES
Warwick Anderson
Pages: 64 - 65
It is a fortunate paradox that research motivated simply by a wish to better understand the natural world can later result in the most powerful applications imaginable. By definition, the outcome of any research is unknown until the research is finished. The outcomes are even less predictable at the...
Conference Abstract
7.10 AORTIC STIFFNESS AND BODY MASS INDEX (BMI) IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)
Nichola Gale, Ali Albarrati, Margaret Munnery, Dennis Shale, John Cockcroft
Pages: 64 - 65
Background: Patients with COPD have increased Cardiovascular (CV) risk and commonly present with altered body composition. Patients with COPD and a low BMI have poorer health outcomes1, while obesity may increase CV risk2. The aim of this analysis was to explore BMI, CV risk, exercise capacity and systemic...