Part of Springer Nature

Artery Research

+ Advanced search
2992 articles
Conference Abstract

P52 The Long-term Effects of Transcatheter Aortic Valve Implantation on Aortic Stiffness

Vasiliki Gardikioti, Dimitrios Terentes-Printzios, Charalambos Vlachopoulos, Konstantinos Toutouzas, Evangelia Christoforatou, Maria Xanthopoulou, Georgios Benetos, Georgios Latsios, Gerasimos Siasos, Evangelia Mpei, Manolis Vavuranakis, Dimitrios Tousoulis
Pages: S93 - S93
Purpose/Background/Objectives: Aortic stiffness and hemodynamics are independent predictors of adverse cardiovascular events. Transcatheter aortic valve implantation (TAVI) is growingly used in high surgical risk patients with aortic valve stenosis. We sought to investigate the effect of TAVI on aortic...
Conference Abstract

P53 More than 2-Year Follow-up of Resistant Hypertensive Patients with Neurovascular Decompression of the Brain Stem on the Left Side

Imola Fejes, Erika Vörös, Pál Barzó, Dóra Bajcsi, Annamária Letoha, Sándor Sonkodi, György Ábrahám, Péter Légrády
Pages: S94 - S94
In the background of resistant hypertension (RHT) the neurovascular pulsatile compression (NVPC) of the left rostral ventrolateral medulla may play a role. In these cases, a neurosurgical decompression (NVD) decreased the blood pressure (BP) and the antihypertensive medication became more effective....
Conference Abstract

P54 Age-specific, Pressure-independent Acute Changes in Carotid-femoral Pulse Wave Velocity During Head-up Tilt

Giacomo Pucci, Alberto Avolio, Bart Spronck, Gaetano Vaudo, Fabio Anastasio, Anton H. Van den Meiracker A.H, Francesco U.S. Mattace-Raso
Pages: S95 - S95
Introduction: Acute, gravity-induced blood pressure (BP) changes during head-up tilt may generate concomitant variations in carotid-femoral pulse wave velocity (cf-PWV). We aimed to separate the pressure-dependent and -independent components of cf-PWV changes observed during head-up tilt. Methods: 30...
Conference Abstract

P55 Remote Ischaemic Preconditioning Reduces Cardiac Biomarkers During Vascular Surgery

Teele Kepler, Karl Kuusik, Urmas Lepner, Joel Starkopf, Mihkel Zilmer, Jaan Eha, Kaido Paapstel, Jaak Kals
Pages: S96 - S96
Objectives: The primary aim of this study was to evaluate the effects of remote ischaemic preconditioning (RIPC) on preventing the leakage of cardiac damage biomarkers in patients undergoing vascular surgery. Methods: Randomised, sham-controlled, double-blinded, single-centre study has been carried...
Conference Abstract

P56 Renal Endovascular Interventions in Szeged Nephrology-Hypertension Center Between 2007–2016

Péter Légrády, Bernadett Nádasdi, Annamária Letoha, Alexandra Gyói, Dóra Bajcsi, Kypros Constantinou, Imola Fejes, Endre Nagy, Tibor Szakál, Erika Vörös, Sándor Sonkodi, György Ábrahám
Pages: S97 - S97
There is no consensus on the antihypertensive effect and on the ability to preserve kidney function of ballon dilatations and/or stent implantation these in renal artery stenosis. From 2007 to 2016 at the 1st Department of Medicine, Nephrology-Hypertension Center, University of Szeged, total of 80 patients...
Conference Abstract

P57 In Patients with Chronic Descending Aorta Dissection the Maximum Systolic Flow Deceleration Rate in the False Lumen is Associated with Aortic Dilatation: a 4D-flow MRI Study

Andrea Guala, Aroa Ruiz-Muñoz, Lydia Duz-Santoy, Gisela Teixido-Tura, Chiara Granato, Augusto Sao-Aviles, Lucia La Mura, Angela Lopez-Sainz, Maria Luz Servato, Arturo Evangelista, Ignacio Ferreira, Jose Rodriguez-Palomares
Pages: S98 - S98
Background: Aortic type B dissection is a life-threating condition in which blood flows between aortic wall layers. Despite a role for morphological variables, such as entry tear location and dimension, in the prediction of progressive false lumen (FL) dilation has been suggested, the role of flow characteristics...
Conference Abstract

P58 Structured Exercise Training is Associated with Better Post Occlusive Reactive Hyperaemia in Skeletal Muscle Measured using Near Infrared Spectroscopy (NIRS)

Chirag Rao, Siana Jones, Khadija Ezzi, Alun Hughes
Pages: S99 - S99
Background: Participation in structured exercise training may improve microvascular function. Post occlusive reactive hyperaemia (PORH) is a measure of microvascular function in skeletal muscle and can be assessed using near-infrared spectroscopy (NIRS). We examined PORH following a short and a long...
Conference Abstract

P59 Marked Differences in Cerebral Haemodynamics Obtained with Transcranial Doppler vs. 2-D Angle-corrected Ultrasound

Christopher Brown, Mahfoudha Al Shezawi, Laura Watkeys, Maggie Munnery, Christopher Pugh, Eric Stöhr, Barry McDonnell
Pages: S100 - S100
Introduction: The assessment of middle cerebral artery (MCA) haemodynamics is essential for the diagnosis and monitoring of cerebrovascular disease. However, conventional transcranial Doppler (TCD) may not capture the correct flow velocities because of sub-optimal angles of insonation. Conversely, 2-D...
Conference Abstract

P60 Invasive Validation of Antares, a New Algorithm to Calculate Central Blood Pressure from Oscillometric Upper Arm Pulse Waves

Marcus Doerr, Stefan Richter, Siegfried Eckert, Marc-Alexander Ohlow, Fabian Hammer, Astrid Hummel, Vivien Dornberger, Elisabeth Genzel, Johannes Baulmann
Pages: S101 - S101
Background: Antares is an algorithm for pulse wave analysis (PWA) by oscillometric blood pressure monitors in order to estimate central (aortic) blood pressure (cBP). Antares aims to enable brachial cuff-based blood pressure (BP) monitors to be type II-devices, determining absolute cBP values independently...
Conference Abstract

P61 Comparison of Two Oscillometric Technics for Measuring Pulse Wave Velocity

Béla Benczúr, Renata Bocskei, Attila Cziraki
Pages: S102 - S102
It has been proven that aortic pulse wave velocity (aoPWV), the measure of arterial stiffness is a strong and independent predictor of both cardiovascular events and all-cause mortality. Beyond the “gold standard” cfPWV (carotid-femoral) a plenty of methods are available for measuring PWV but the interpretation...
Conference Abstract

P62 Estimation of Wave Intensity in Humans Using only Pressure Waveforms and Reservoir Analysis

Alun Hughes, Kim Parker, Nish Chaturvedi, Chloe Park
Pages: S103 - S104
Background: Measurement of wave intensity (WI) requires simultaneous or quasi-simultaneous measurement of pressure and flow limiting its use. Previous work in dogs [1] and humans [2] has shown that the excess pressure waveforms calculated using reservoir analysis correspond closely with aortic flow waveforms....
Conference Abstract

P63 Accuracy (Validation) of Central Blood Pressure Measurement Using the Sphygmocor Xcel-cuff Device

Martin Schultz, Dean Picone, Matthew Armstrong, Andrew Black, Nathan Dwyer, Philip Roberts-Thomson, James Sharman
Pages: S105 - S105
Background: Numerous devices purport to measure central aortic BP as distinct from conventional brachial BP. This study aimed to determine the accuracy (validation) of the Sphygmocor Xcel-cuff device (AtCor Medical, Sydney, Australia) for measuring central BP. Methods: 330 patients (mean age 61.3 ±...
Conference Abstract

P64 Carotid Artery Tracking with Automated Wall Position Resets Yields Robust Distension Waveforms in Long-term Ultrasonic Recordings

Fabian Beutel, Laura Mansilla Valle, Chris Van Hoof, Evelien Hermeling
Pages: S106 - S107
Background: Carotid artery tracking has high clinical relevance for the investigation of arterial stiffness indicators like Pulse Wave Velocity (PWV). However, current tracking systems are unreliable and/or not fully automated [1,2]. In this work we propose a novel wall tracking algorithm for long-term...
Research Article

P65 A Beat-to-Beat Quality Indicator Based on Piecewise Spatiotemporal Estimates of Carotid Pulse Wave Velocity Improves Correlation with Pulse Pressure

Fabian Beutel, Chris Van Hoof, Evelien Hermeling
Pages: S108 - S109
Background: Local carotid pulse wave velocity (PWV) estimation is challenging due to a complex anatomy and associated wave reflections [1]. Wave interference is both blood pressure (BP) and position dependent, hence causing nonlinearity in the spatiotemporal PWV estimation [2]. In lack of beat-to-beat...
Conference Abstract

P66 Mathematical Model of the Renal Microcirculation and Effects of Chronic Kidney Disease

Nikolaos Fountoulakis, Karla Sanchez-Cazares, Kim Parker, Janaka Karalliedde
Pages: S110 - S110
Background: Diabetes is one of the leading causes of chronic kidney disease (CKD) worldwide. CKD is directly linked to increased morbidity and mortality. The role of vascular changes in diabetes and underlying mechanism of kidney disease is not well understood. Methods: We present a mathematical model...
Conference Abstract

P67 Detecting Preload Reduction with Machine Learning on Arterial Waveform Parameters

Björn van der Ster, Marije Wijnberge, Marthe Huntelaar, Job de Haan, Koen van der Sluijs, Denise Veelo, Berend Westerhof
Pages: S111 - S111
Background: Hemodynamic optimization of unstable patients by means of fluid resuscitation improves patient outcome, but choosing the correct amount of fluid can be difficult. Too little fluid may not ensure adequate perfusion whereas too much fluid is associated with increased mortality. Static parameters...
Conference Abstract

P68 Usefulness of an Optimal Cut-off in Central Augmentation Pressure for the Detection of Left Ventricular Hypertrophy in Men

Masakazu Obayashi, Shigeki Kobayashi, Hirotaka Yamamoto, Yoriomi Hamada, Takumi Nanno, Michihiro Kohno, Masafumi Yano
Pages: S112 - S112
Background: Recently, we showed an age-related increase in augmentation pressure (AP) measured using Mobil-O-Graph (MOG) in normotensive Japanese individuals. However, AP might be a poor index of wave reflection due to the overlap between the forward wave and reflected wave. Methods: We enrolled untreated...
Conference Abstract

P69 The Initial Upstroke Time is Most Strongly Associated with the Severity of as Among Brachial Pulse Wave Parameters

Masao Takahashi, Kyohei Fukatani, Tomoyuki Kabutoya, Satoshi Hoshide, Tatsuya Yoneyama, Tetsuya Ito, Kazuomi Kario
Pages: S113 - S113
Background: Aortic valve stenosis (AS) is the most common valve disease in an elderly population, therefore, simple screening examination for AS is needed. Although a prolonged carotid upstroke time (UT), and prolonged ejection time (ET) of a brachial pulse wave (BPW) have been observed in severe AS...
Conference Abstract

P70 Effects of Different Vitamin D Status on Mechanical, Pharmacological and Histological Characteristics of Coronary Arterioles in Male Rat Model

Reka Eszter Sziva, Zoltan Fontanyi, Eva Pal, Leila Hadjadj, Anna Monori-Kiss, Eszter Maria Horvath, Rita Benko, Attila Magyar, Andrea Heinzlmann, Zoltan Benyo, Gyorgy L. Nadasy, Szabolcs Varbiro, Bálint Bányai
Pages: S114 - S114
Objectives: The cardiovascular/CV risk is higher in males. To know better these increased risks, our aim was to investigate the effects of different vitamin D/VD status on mechanical, pharmacological and histological characteristics of coronary arterioles in male rat model. Methods: In male Wistar-rats...
Conference Abstract

P71 The Interrelationship Between the Alteration of Arterial Markers and Left Ventricular Diastolic Dysfunction in Metabolic Syndrome Subjects

Svetlana Solovjova, Ligita Ryliskyte, Jelena Celutkiene, Jolita Badariene, Aleksandras Laucevicius
Pages: S115 - S115
We aimed to determine how the alteration of arterial stiffness (AS) affects the dynamics of left ventricular (LV) diastolic dysfunction (DD) in metabolic syndrome (MetS) subjects during longitudinal observation (3.8 ± 0.6 years). Methods: A follow-up study was carried out in 573 (53.4 ± 5.8 years, 211...
Conference Abstract

P72 Vascular Aging Prediction in High Cardiovascular Risk Cohort

Agne Laucyte-Cibulskiene, Ligita Ryliskyte, Milda Kovaite, Laurynas Rimsevicius, Laura Balkeviciene, Jolita Badariene, Aleksandras Laucevicius
Pages: S116 - S116
Aim: To assess a time-dependent change of arterial stiffness gradient (PWVratio calculated by dividing carotid-femoral to carotid-radialPWV), a marker of vascular aging, in high cardiovascular risk cohort. Methods: This cohort study (n = 689) was conducted during the period 2010–2019 at Vilnius University...
Conference Abstract

P73 The Relationship Between Different Measurements of Arterial Stiffness

Eszter Szabó, Krisztina Gáspár, Ildikó Szabó, Viktória Kovács, Zsuzsanna Pál, Gábor Simonyi, Endre Kolossváry, Katalin Farkas
Pages: S117 - S117
Background: Arterial stiffness is the characteristic of early vascular damage that can be measured by several methods. Sphygmocor determines the carotid-femoral pulse wave velocity (PWV). Cardio-ankle vascular index (CAVI) also measures PWV between heart and ankle, independently of blood pressure. According...
Conference Abstract

P74 Validation of Surface Distance Measurement by MRI for Pulse Wave Velocity in Children

Adrienn Bárczi, Arianna Dégi, Orsolya Cseprekál, Eva Kis, Ádám Szabó, Gábor Rudas, George S Reusz
Pages: S118 - S118
Background: Aortic pulse wave velocity (PWV) is the gold standard measurement for arterial stiffness. Normative values exist for PWV in children using the subtracted method (LSM) for the estimation of the distance, however no imaging validation studies in the growing pediatric population. The formula...
Conference Abstract

P76 Carotid Artery Disease in Patients with Newly Diagnosed, Untreated Familial Hypercholesterolemia

Bíborka Nádró, Beáta Kovács, Ágnes Diószegi, Lilla Juhász, Dénes Páll, György Paragh, Mariann Harangi
Pages: S119 - S119
Familial hypercholesterolemia (FH) patients are characterized by markedly elevated LDL-cholesterol (LDL-C) concentration, positive family history of hypercholesterolemia and premature vascular complications including carotid artery disease (CAAD). Carotid plaques are associated with atherosclerosis of...
Conference Abstract

P77 Long-term Effects of LDL Apheresis on Carotid Arterial Atherosclerosis in Two Severe Heterozygous Familial Hypercholesterolemic Patients

Ágnes Diószegi, Lilla Juhász, Bíborka Nádró, György Paragh, László Oláh, Dénes Páll, József Balla, Mariann Harangi
Pages: S120 - S120
The long-term effects of low-density lipoprotein (LDL) apheresis (LA) on the progression and regression of atherosclerosis were evaluated by carotid ultrasonography in two severe heterozygous familial hypercholesterolemic patients with carotid artery stenosis. Furthermore, the lipid-lowering efficacy...
Conference Abstract

P78 Endothelial Dysfunction and Arterial Stiffness During Type 2 Diabetes

Maimouna Toure, Magid Hallab, Souleymane Thiam, Sheikh AB Mane, Farid Belem, Abdoulaye Samb
Pages: S121 - S121
Objective: We aimed to study Endothelial dysfunction and Arterial Stiffness in Diabetes mellitus. Methods: 29 women with type 2 diabetes and 8 non-diabetic controls were included. Vascular function was studied with pOpmetre® (Axelife SAS-France) to assess the foot to toe Pulse Wave Velocity; and EndoPAT2000®...
Conference Abstract

P79 Non-invasive Estimation of Central Pressures in Abdominal Aortic Aneurysm Patients and Changes in PWV After EVAR

Suzanne Holewijn, Lennart van de Velde, Jenske Vermeulen, Michel Reijnen
Pages: S122 - S122
Background: Abdominal aortic aneurysm (AAA) disease is mainly treated by endovascular aneurysm repair (EVAR) and PWV has been shown to increase after EVAR. Arterial stiffness is predictive of cardiovascular disease, but has not been investigated in AAA-patients. We investigated if central pressures (CP)...
Conference Abstract

P80 Predictors of Middle Cerebral Artery Pulsatility Index in Chronic Obstructive Pulmonary Disease and Healthy Controls; Data from the ACRADE Study

Mahfoudha Al Shezawi, Maggie Munnery, John Cockcroft, Laura Watkeys, Eric Stohr, Nichola Gale, Barry McDonnell
Pages: S123 - S123
Background: Chronic obstructive pulmonary disease (COPD) is characterised by airway limitation which is an independent predictor of increased cardiovascular (CV) risk and mortality [1]. COPD is associated with increased arterial stiffness [2] and increased incidence of all stroke subtypes [3]. However,...
Research Article

P81 Antibody to Cardiotonic Steroid Reduces Blood Pressure and Vascular Fibrosis in Preeclampsia

N.I. Agalakova, V.A. Reznik, O.V. Nadei, I.A. Ershov, O.S. Rassokha, M.L. Vasyutina, M.M. Galagudza, A.Y. Bagrov
Pages: S124 - S124
Background: Previous studies implicated cardiotonic steroids, including Na/K-ATPase inhibitor marinobufagenin (MBG), in the pathogenesis of preeclampsia (PE). We demonstrated that MBG induces fibrosis via mechanism involving inhibition of Fli1, a nuclear transcription factor and a negative regulator...
Conference Abstract

P82 Impaired Skin Microvascular Function in Systemic Lupus Erythematosus

Nikolaos Koletsos, Eugenia Gkaliagkousi, Antonios Lazaridis, Panagiota Anyfanti, Areti Triantafyllou, Konstantina Dipla, Panagiotis Dolgyras, Vasiliki Galanopoulou, Spyros Aslanidis, Stella Douma
Pages: S125 - S125
Objectives: Alterations in skin microcirculation have been associated with damage in various microvascular beds [1]. Endothelial dysfunction in microcirculation plays a central role in the pathophysiology of rheumatic diseases, contributing substantially to the increased cardiovascular risk of these...
Conference Abstract

P83 Effect of Aging on the Aortic Reservoir and Excess Pressure in Normal Humans

Tetsu Yamakado, Hideyoshi Ko
Pages: S126 - S126
Background: Reservoir pressure analysis has been newly introduced to analyze arterial waveform and function. There are few data regarding the effect of aging on the aortic reservoir and excess pressures in normal humans. Objectives and Methods: To investigate this issue, we analyzed high-fidelity aortic...
Conference Abstract

P84 Prediction of Cardiovascular Events and Mortality by Pulse Wave Velocity: a Comparison of Invasive Measurements and Noninvasive Estimation Methods

Bernhard Hametner, Siegfried Wassertheurer, Christopher Clemens Mayer, Kathrin Danninger, Ronald Binder, Thomas Weber
Pages: S127 - S127
Introduction: Arterial properties are linked to the presence and severity of coronary artery disease (CAD). Coronary blood flow is strongly and inversely related to arterial stiffness. Thus, the aim of this prospective study was to evaluate the prognostic value of PWV in high-risk patients with suspected...
Conference Abstract

P85 Acute Systemic Inflammation Reduces both Carotid and Aortic Wave Reflection in Young Healthy Adults

Elizabeth Schroeder, Wesley Lefferts, Thessa Hilgenkamp, Bo Fernhall
Pages: S128 - S128
Acute inflammation increases the risk of cardiac and cerebrovascular events, potentially associated with altered hemodynamic load. Wave reflection at the aorta and carotid artery can contribute to central hemodynamic load and provide insight into downstream changes in vascular tone. Acute inflammation...
Conference Abstract

P86 Can Central Blood Pressure be Accurately Estimated in Individuals with and Without Systolic Blood Pressure Amplification?

Goupil Remi, Cédric Kowalski, Florence Lamarche
Pages: S129 - S129
Introduction: Systolic blood pressure (SBP) does not always amplify from central to peripheral arteries. Individuals without SBP amplification (SBPamp) have higher aortic blood pressure (BP) despite similar brachial cuff SBP. To circumvent this discrepancy, the aim of this study was to determine if aortic...
Conference Abstract

P87 Ultra–high Frequency Ultrasound Assessment in Vascular Ehlers Danlos Syndrome: a Validation and Reproducibility Study

Rosa Maria Bruno, Magdalini Alexopoulou, Hakim Khettab, Xavier Jeunemaitre, Pierre Boutouyrie
Pages: S130 - S130
Background: In patients with Vascular Ehlers-Danlos syndrome (vEDS), an abnormally low carotid intima-media thickness (CIMT) may increase the risk of arterial dissection and rupture. Thus its accurate assessment by ultra–high frequency ultrasound (UHFUS), thanks to its higher spatial resolution, may...
Conference Abstract

P88 Improvement in Functional Capacity with Spironolactone Masks the Treatment Effect on Exercise Blood Pressure

Myles Moore, Martin Schultz, James Hare, Thomas Marwick, James Sharman
Pages: S131 - S131
Background: A hypertensive response to submaximal exercise is associated with cardiovascular disease but may be influenced by functional capacity. Spironolactone may improve functional capacity, which could mask treatment effects on exercise blood pressure (BP). This study sought to examine this hypothesis. Methods:...
Conference Abstract

P89 Non-invasive Blood Pressure Measurement System Using Three-axis Tactile Force Sensor

Hae-Young Lee
Pages: S132 - S132
Blood pressure is most important parameter reflecting hemodynamic factors, however it is continuously variable in 24 hours. Here, we made a non-invasive and continuous BP measurement device using a three-axis tactile force sensor. All the data was collected every 2 min for the short-term experiment,...
Conference Abstract

P90 Indexing Left Ventricular Mass to Body Size: Which Method is the Most Appropriate in Early Adulthood?

Hannah Taylor, Chloe Park, Abigail Fraser, Laura Howe, Dianna Ferreira, Nic Timpson, Debbie Lawlor, George Davey-Smith, Nishi Chaturvedi, Alun Hughes
Pages: S133 - S133
Introduction: Left ventricular mass (LVM) predicts cardiovascular risk. In early life, LVM is conventionally indexed to height 2.7 [1], although this may not account for sex differences in growth. We investigated allometric scaling of LVM to height, lean mass (LM) and body surface area (BSA) in a UK...
Conference Abstract

P92 The Association of Agreeableness and Conscientiousness with 24-Hour Brachial Blood Pressure and Hemodynamic Parameters in Untreated Hypertensive Patients

Milán Vecsey-Nagy, Beáta Kőrösi, Dóra Batta, Xénia Gonda, Zoltán Rihmer, Zsófia Nemcsik-Bencze, Andrea László, János Nemcsik
Pages: S134 - S134
Background: There is growing evidence that Five Factor Model personality traits (extraversion agreeableness, conscientiousness, neuroticism, and openness) have an impact on cardiovascular (CV) risk. The aim of our study was to evaluate their associations with 24-hour brachial and central hemodynamic...
Conference Abstract

P93 Relationship Between Central Pressure and Urinary Sodium Excretion in a Population-based Study in Salvador, Brazil, Preliminary Results

Roberta de Castro, Lucélia Magalhães, Danielle Brustolim, Diorlene da Silva, Antonio Filho, Larissa Bessa,
Pages: S135 - S135
Introduction: Central pressure (CP) has shown to be more reliable than cardiovascular mortality; salt intake in the diet is directly related to the increase in CP. Methods: A population-based cross-sectional study representative of a neighborhood of Salvador-BA, Brazil, distributed in 12 census tracts...
Conference Abstract

P94 Relationship Between Central Pressure and Potassium Urinary Excretion in a Population-Based Study in Salvador, Brazil, Preliminary Results

Antonio Filho, Lucélia Magalhães, Danielle Brustolim, Diorlene da Silva, Roberta de Castro, Larissa Bessa,
Pages: S136 - S136
Introduction: Central pressure (CP) has been shown to be more reliable in cardiovascular mortality than peripheral. Previous studies correlate the relationship between CP increase and urinary potassium excretion. Methods: A population-based cross-sectional study representative of a neighborhood of Salvador-Ba,...
Conference Abstract

P96 Soluble Receptor for Advanced Glycation End-products Independently Influenced Individual Age-dependent Increase of Arterial Stiffness

Július Gelžinský
Pages: S137 - S137
Background: Soluble receptors for advanced glycation end-products (sRAGEs) have been suggested to have a protective role neutralizing the advanced glycation end-products (AGEs) and their pathological effect on vessel walls. We aimed to investigate the association between circulating concentrations of...
Conference Abstract

P97 Age Modifies the Relationship Between Arterial Stiffness, Adiposity and Blood Pressure from Adolescence to Adulthood in Men and Women

Chloe Park, Marietta Charakida, Laura Howe, Abigail Fraser, Alicja Rapala, Suzanne Williams, Siana Jones, John Deanfield, Nish Chaturvedi, Alun Hughes
Pages: S138 - S138
Introduction: Adult obesity is associated with greater arterial stiffness however in youth the relationship is unclear. We investigated associations between arterial stiffness and adiposity and explored the contribution of blood pressure from adolescence to emerging adulthood (17–24 yrs). Methods: 3885...
Conference Abstract

P98 Impaired Pulmonary Function is Associated with Increased Cardio-ankle Vascular Index in Hiv Patients in Ghana

Kwame Yeboah, Latif Musah, Samuel Essel, Bartholomew Dzudzor, J Kennedy Cruickshank
Pages: S139 - S139
Aim: Patients with HIV have increased cardiovascular risk and pulmonary defects. We investigated the association between impaired pulmonary function (IPF) and arterial stiffening measured by the cardio-ankle vascular index (CAVI) in Ghanaian HIV patients. Method: Spirometry was used to measure pulmonary...
Conference Abstract

P101 Arterial Stiffness vs Sarcopenia in Portuguese Elderly Population

Valentina Vassilenko, Andreia Serrano, Beatriz Ramalho, Paulo Bonifácio, Ana C. Coelho, Fernando Pimentel-Santos
Pages: S140 - S140
Aging often results in the appearance of sarcopenia, which is characterized by loss of muscle mass and strength. The incidence of sarcopenia in the elderly is a quite common and leads to weakness and disability, as well as a lower quality of life, also assuming a high social and economic impact. One...
Conference Abstract

P102 Large Artery Stiffness is Associated with Lower Brain pH and Memory Performance in Middle-aged and Older Adults

Lyndsey DuBose, Vincent Magnotta, David Moser, Gary Mitchell, Virginia Nuckols, Ryan Ward, Gary Pierce, Laura Boles Ponto
Pages: S141 - S141
Background/Objectives: Large artery stiffening is a novel risk factor for cognitive impairment including Alzheimer’s disease. Loss of impedance mismatch between central and cerebral arteries promotes cerebrovascular dysfunction via chronic transmission of excessive pulsatile pressure and flow to the...
Conference Abstract

P103 Improved Metabolic Vasoreactivity in the Brain of HM3 Patients and its Underlying Microcirculatory Mechanisms

Eric J. Stöhr, Ruiping Ji, Koichi Akiyama, Francesco Castagna, Pinsino Alberto, John Cockcroft, Melana Yuzefpolskaya, Reshad Garan, Veli Topkara, Hiroo Takayama, Koji Takeda, Yoshifumi Naka, Paolo Colombo, Joshua Willey, Barry J. McDonnell
Pages: S142 - S143
Background: The MOMENTUM3 trial1 has revealed superiority of the novel HeartMate3 (HM3) left ventricular assist device (LVAD) compared with the HM2, with a significantly reduced occurrence of cerebrovascular accidents. Thus, cerebral autoregulation may be improved in HM3 compared with HM II patients,...
Conference Abstract

P104 White Coat Hypertension is Associated with Increased Small Vessel Disease in the Brain

Fran Kirkham, E Drazich, A Vundavalli, P Rankin, J Timeyin, E Bunting, K Ali, C Rajkumar
Pages: S144 - S144
Objective: Small vessel disease, measured by brain white matter hyperintensity (WMH), is associated with increased stroke risk and cognitive impairment. This study aimed to explore the relationship between WMH on computerised tomography (CT) and white coat hypertension (WCH) in patients with recent transient...
Conference Abstract

P105 Photoplethysmographic Signals Analysis Before, During, and After the Finnish Sauna Exposures

Matti Huotari
Pages: S145 - S145
Wellness and healthiness depend on physiology if no illness exists in the body. As a treatment either in healthy or sick state, we suggest that sauna exposure could be good for cardiovascular disease (CVD) prevention, especially heart and brains arteries. We measured by our photoplethysmographic (PPG)...
Conference Abstract

P106 Effect of Açaí-Juçara on Central Pressure in Individuals with Overweight or Obesity

Tainah Ortiz, Fernanda Gorski, Tatiana Lehnen, Liliana Boll, Bruna Eibel, Alexandre Lehnen, Eduardo Barbosa
Pages: S146 - S146
Introduction: Açaí-juçara is a fruit with a antioxidant content that can modify the vascular environment and attenuate the effects of obesity. Objective: To evaluate the effect of açaí-juçara on pulse pressure parameters in overweight or obese individuals. Methods: Randomized clinical trial with 23...
Conference Abstract

P107 Endothelial Dysfunction Associated with Arterial Stiffness in Postmenopausal Women with Obesity

Patricia Lizette Ramírez Soltero, Leonel García Benavides, Marycruz Barocio Pantoja, Brandon Giovanni Illescas Vidrio, David Cardona Müller, Ernesto Germán Cardona Muñoz, Sylvia Elena Totsuka Sutto
Pages: S147 - S147
Background: Endothelial dysfunction (ED) represents an initial step of “vascular failure” [1]; several factors affect the functionality of the endothelium. Obesity [2] and estrogen deficiency [3] are independently associated with this. The early detection of ED is essential to intervene and prevent its...
Conference Abstract

P108 Relation Between Abdominal Aorta and Carotid Artery Responses to Sympathetic Stimulation using Duplex Ultrasound

Anne-Jet Jansen, Jenske Vermeulen, Suzanne Holewijn, Dick Thijssen, Michel Reijnen
Pages: S148 - S148
Background: Sympathetic stimulation in central arteries, such as the carotid artery, lead to vasodilation in healthy subjects and vasoconstriction in those with cardiovascular disease. Moreover, this response has independent prognostic value for future events. Whether the aorta demonstrates similar responsiveness...
Conference Abstract

P109 The Influence of Sex on Cuff Blood Pressure Accuracy

Elif Stoneman, Dean Picone, Martin Schultz, Matthew Armstrong, Willem Bos, Nathan Dwyer, Peter Lacy, Esben Laugesen, Stefano Omboni, Giacomo Pucci, Philip Roberts-Thomson, George Stouffer, Kenji Takazawa, Thomas Weber, Berend Westerhof, James Sharman
Pages: S149 - S149
Background: Cuff blood pressure (BP) is intended to approximate central aortic BP and accuracy is paramount. Sex differences in BP physiology could influence the accuracy of cuff BP as an estimate of invasive aortic BP, but this has not been explored in-depth and was the aim of this study. Methods:...
Conference Abstract

P110 Impact of Cardiac Pre-load on Arterial Stiffness in Patient with Essential Hypertension

Luca Faconti, Ryan McNally, Bushra Farukh, Phil Chowienczyk
Pages: S150 - S150
Background: Effects of afterload and blood pressure (BP) on pulse wave velocity (PWV) have been investigated using vasoactive drugs but effects of cardiac pre-load have not previously been studied. Methods: Transient mechanical reduction of cardiac pre-load (lower limb venous occlusion, LVO) and expansion...
Conference Abstract

P111 Arterial Stiffness and Unattended and Attended BP Values

Anna Paini, Carlo Aggiusti, Fabio Bertacchini, Deborah Stassaldi, Sara Capellini, Enrico Agabiti Rosei, Maria Lorenza Muiesan, Massimo Salvetti
Pages: S151 - S151
Measurement of “unattended” blood pressure (BP) may reduce or eliminate the “white coat effect”. Despite the possible advantages of this approach for BP measurement, only few studies analysed the relationship between unattended BP and cardiovascular events or with hypertension mediated organ damage (HMOD)....
Conference Abstract

P112 Influence of Cuff Blood Pressure Accuracy on Identification of Isolated Systolic Hypertension

Dean Picone, Martin Schultz, Matthew Armstrong, Willem Bos, Nathan Dwyer, Peter Lacy, Esben Laugesen, Stefano Omboni, Giacomo Pucci, Philip Roberts-Thomson, George Stouffer, Kenji Takazawa, Thomas Weber, Berend Westerhof, James Sharman
Pages: S152 - S152
Introduction: Isolated systolic hypertension (ISH) is the most common form of hypertension in older people. However, accurate identification of ISH may be hindered because cuff blood pressure (BP) underestimates systolic BP (SBP) and overestimates diastolic BP (DBP). This study aimed to determine the...
Conference Abstract

P113 The Forgotten Black Box of Blood Pressure: Error in Oscillometric Mean Arterial Pressure is Associated with Cuff Measurement Inaccuracy

Dean Picone, Martin Schultz, Matthew Armstrong, Nathan Dwyer, Philip Roberts-Thomson, Thomas Weber, James Sharman
Pages: S153 - S153
Background: Accurate measurement of cuff systolic BP (SBP) and diastolic BP (DBP) is contingent on the assumption of oscillometric MAP being accurate. If MAP is inaccurate this is likely to impact the accuracy of cuff SBP and DBP, but this has never been determined and was the aim of the study. Methods:...
Conference Abstract

P114 “Stifflammation” is an Essential Cause of Cardiovascular Hospitalizations in Hypertensives

Georgia Christopoulou, Charalambos Vlachopoulos, Lambros Korogiannis, Dimitrios Terentes-Printzios, Evangelia Sigala, Iosif Koutagiar, Vasiliki Gardikioti, Dimitrios Tousoulis
Pages: S154 - S154
Purpose/Background/Objectives: Hypertension is associated with increased cardiovascular risk, inflammation and arterial stiffness. We sought to investigate the role of inflammation and arterial stiffness in the prognosis of cardiovascular hospitalization in hypertensives patients over an extensive follow-up. Methods:...
Conference Abstract

P115 Does Post-stroke White Coat Hypertension/Effect (WCH/E) Require Intensive Blood Pressure Management?

Fran Kirkham, GN Nuredini, A Saunders, Erin Drazich, Eva Bunting, Philip Rankin, K Ali, M Okorie, Chakravarthi Rajkumar
Pages: S155 - S155
Objective: International guidelines advocate conservative management of post-stroke white coat hypertension. The aims of this study were to investigate; i) does WCH/E result in increased stroke risk? and ii) is WCH/E associated with surrogate markers of cardiovascular risk? Methods: The Arterial Stiffness...
Conference Abstract

P116 Post-stroke White Coat Hypertension/Effect is Associated with Greater Arterial Stiffness

Fran Kirkham, A Saunders, GN Nuredini, E Drazich, Philip Rankin, E Bunting, K Ali, M Okorie, C Rajkumar
Pages: S156 - S156
Objective: White coat hypertension/effect (WCH/E) describes an elevated clinic blood pressure (BP) with normal daytime ambulatory BP (ABPM) values. It is not clear whether WCH/E is associated with adverse vascular risk. This study aimed to determine the relationship between WCH/E and arterial stiffness...
Conference Abstract

P117 Case Report of a Patient with Extreme Reverse Dipping Phenomenon Decades After Kidney Transplantation

Dóra Batta, Beáta Kőrösi, Zsófia Nemcsik-Bencze, János Nemcsik
Pages: S157 - S157
A patient with the complaint of moderately elevated blood pressure came to our office. Important data in his history was kidney transplantation in 1985, due to glomerulonephritis and since that time he was in regular nephrology care. He also had chronic lumboischialgia, chronic hypertension and stage...
Conference Abstract

P118 Arterial Stiffness in Patients with Arterial Hypertension on Short Term Dual Treatment with Fimasartan/Amlodipine

Brandon Giovany Illescas Vidrio, David Cardona Müller, Ernesto Germán Cardona Muñoz, Claudia Yanette Gálan Ruiz, Carlos Gerardo Ramos Becerra, Fernando Grover Páez
Pages: S158 - S158
Background: Pulse wave velocity (PWV) reflects arterial stiffness and is an independent predictor of cardiovascular mortality and morbidity. It is important to determine the effect dual therapy has on both BP and PWV. Methods: A quasi-experimental study was performed in patients with grade 1 and 2 primary...
Conference Abstract

P119 Carotid Stiffness is Strongly Associated with Skin Microvascular Dysfunction in Normotensives and Newly-diagnosed Hypertensives

Antonios Lazaridis, Eugenia Gkaliagkousi, Nikolaos Koletsos, Eleni Gavriilaki, Panagiota Anyfanti, Barbara Nikolaidou, Areti Triantafyllou, Konstantina Dipla, Stella Douma
Pages: S159 - S159
Background/Objectives: Skin microcirculation represents an easily accessible window reflecting generalized microvascular dysfunction. It has been correlated with alterations in several microvascular beds, though evidence regarding its association with macrovascular damage is scarce. Carotid artery stiffening...
Conference Abstract

P120 Early Sympahovagal Imbalance Associates with Future Arrhythmic Events in Hypertensives

Dimitrios Terentes-Printzios, Charalambos Vlachopoulos, Georgia Christopoulou, Lampros Korogiannis, Panos Xydis, Vasiliki Gardikioti, Eirini Solomou, Nikolaos Ioakeimidis, Christos Georgakopoulos, Ioanna Dima, Dimitrios Tousoulis
Pages: S160 - S160
Purpose/Background/Objectives: Cardiac autonomic dysfunction is associated with increased cardiovascular mortality and arrhythmias. The aim of the study was to investigate the effect of heart rate variability (HRV) in the prognosis of future arrhythmic events. Methods: We studied 292 untreated at baseline...
Conference Abstract

P121 Background of the Development of Carotid and Femoral Atherosclerotic Plaques in Twins

David Laszlo Tarnoki, Helga Szabo, Kata Gyulay, Zsofia Jokkel, Rebeka Debreceni, Greta Janositz, Anita Hernyes, Viktor Berczi, Adam Domonkos Tarnoki
Pages: S161 - S161
Introduction: Development of carotid and femoral atherosclerotic plaques proved to be heritable in previous studies. However, no comprehensive ultrasonographic evaluation of the volume and types of plaque has been performed. Methods: Comprehensive carotid and femoral arterial ultrasound examination...
Conference Abstract

P122 Unrealistic Pulse Pressures from Calibrated Tonometric Waveforms

Koen Reesink, Louise Marais, Pierre Boutouyrie
Pages: S162 - S162
Background: Calibration of carotid artery tonometry waveforms needs to account for pulse pressure augmentation [1]. Due to its location nearer to the heart, carotid pulse pressure (carPP) is about 10 mmHg lower than brachial (brachPP) [1]. In practice, perfect applanation is hard to achieve with tonometry...
Conference Abstract

P123 Beyond Diameters, Flow Hemodynamics Quantified by Magnetic Resonance Imaging to Help Characterizing Aneurysmal Aorta

Sophia Houriez—Gombaud-Saintonge, Ariel Pascaner, Gilles Soulat, Umit Gencer, Thomas Dietenbeck, Damian Craiem, Emilie Bollache, Yasmina Chenoune, Elie Mousseaux, Nadjia Kachenoura
Pages: S163 - S163
Purpose: Referral to surgery in thoracic aortic aneurysms (TAA) is based on maximal diameter (Dmax) measured from imaging, which is known to have a high diagnosis failure rate. In addition to geometry, 4D flow MRI provides a comprehensive time-resolved flow imaging. Thus, our aim was to evaluate the...
Conference Abstract

P124 Impact of Tapering on Arterial Blood Pressure Using a One-dimensional Computational Model

Shima Abdullateef, Jorge Mariscal-Harana, Jordi Alastruey, Ashraf Khir
Pages: S164 - S164
Aortic tapering is a known characteristic of the arterial tree affecting the development of pressure in the aorta. With tapering, the cross-sectional area of vessels decreases moving towards the periphery causing reflections to travel back to the heart. The reflection waves present in the aorta are an...
Conference Abstract

P125 Local Pulse Wave Velocity in the Arterial Tree: Site Matters!

Daimé Campos Arias, Nikos Stergiopulos, Tania Rodríguez Moliner, Patrick Segers
Pages: S165 - S166
Background: Several so-called loop-based methods, have been proposed to estimate local pulse wave velocity (PWV). However, previous studies have demonstrated inaccuracies in local PWV-estimates due to presence of reflections, which led to the proposition of a frequency-domain correction method [1]. The...
Conference Abstract

P126 Characterization of Skin Temperature Changes in Response to Photobiostimulation Using Thermal Imaging: A Thermo-Anatomical Correlation

Oshrit Hoffer, Neta Rabin, Lilach Gavish, Moshe Halak, Ortal Haim, Yuval Shayovitz, Simon Shkilevich, Benjamin Gavish, Yair Zimmer, Zehava Ovadia-Blechman
Pages: S167 - S167
Background and Objective: Infrared Thermal Imaging (ITI) is a noninvasive method to measure skin temperature (ST). The latter is determined by the microcirculatory blood flow and ambient temperature. Photobiostimulation has been shown to increase blood flow. The objective was to characterize the spatial...
Conference Abstract

P127 Graded Cuff Compression Protocol to Induce Retrograde Shear Produces Proportionate Increment in Regional Arterial Compliance in Human Peripheral Artery

Naaz Afreen, Dinu Chandran, Ashok Jaryal, Kishore Deepak, Sitikantha Roy
Pages: S168 - S168
Background: External compression using pneumatic cuff inflation is a well-established model used to induce incremental changes in proximal retrograde flow and shear [1]. The mechanisms behind distal cuff compression leading to proximal increase in retrograde shear are not clear. We hypothesized that...
Conference Abstract

P128 Accuracy of Age-appropriate Transfer Functions in Modelling Central Arterial Waveform Features

Tommy Cai, Meroni Alice, Ahmad Qasem, Mark Butlin, Julian Ayer, David Celermajer, Alberto Avolio, Michael Skilton
Pages: S169 - S169
Background: Central aortic pressure waveforms can be modelled non-invasively in adults using general transfer functions. These techniques have been applied to, but not formally validated in paediatric populations. We recently developed and validated two age-appropriate paediatric transfer functions and...
Conference Abstract

P129 Arterial Stiffness in Bicuspid or Tricuspid Aortic Valve Aortopathy Using Magnetic Resonance Imaging: Crossing the Physical and Hemodynamic limits?

Ariel Pascaner, Sophia Houriez—Gombaud-Saintonge, Gilles Soulat, Umit Gencer, Thomas Dietenbeck, Yasmina Chenoune, Nadjia Kachenoura, Elie Mousseaux, Damian Craiem, Emilie Bollache
Pages: S170 - S170
Purpose: To provide a comprehensive assessment of aortic stiffness, through both local and regional distensibility and pulse wave velocity (PWV), in patients with either a tricuspid (TAV) or bicuspid (BAV) aortic valve and/or aortic dilation using MRI. Methods: We included 18 patients with TAV and dilated...
Conference Abstract

P130 Cardiac Resynchronization Therapy Improves Early Ventricular Contraction and Reduces Time to Onset of Relaxation

Haotian Gu, Simon Claridge, Aldo Rinaldi, Phil Chowienczyk
Pages: S171 - S171
Background: Haemodynamic effects of Cardiac Resynchronisation Therapy (CRT) may be mediated by an improvement in early systolic function, as well as by improvements in overall systolic function. We examined whether CRT improves early ventricular contraction as measured by first-phase ejection fraction...
Conference Abstract

P134 A New Method for Non-invasive Measurement of Arterial Wave Intensity, Speed and Reflection

Ethan Rowland, Kai Riemer, Kevin Lichtenstein, Mengxing Tang, Peter Weinberg
Pages: S172 - S172
Introduction: The ventricles accelerate and decelerate blood; the resulting disturbances propagate through the arterial system as waves. These waves contain clinically useful information: e.g. their magnitude and timing varies with cardiac performance and their speed depends on arterial stiffness. These...
Conference Abstract

P135 Assessment of Novel Blood Pressure Corrected Cardio-ankle Vascular Index in Response to Acute Blood Pressure Changes

Michal Mestanik, Bart Spronck, Alexander Jurko, Andrea Mestanikova, Tomas Jurko, Mark Butlin, Alberto Avolio, Lucia Bona Olexova, Zuzana Visnovcova, Nikola Sekaninova, Ingrid Tonhajzerova
Pages: S173 - S173
Background: Cardio-ankle vascular index (CAVI) has long been considered a measure of arterial stiffness independent of short-term changes in blood pressure (BP) [1]. Recently and theoretically, CAVI was found to be partially affected by actual BP, thus, a novel BP-corrected index, CAVI0, was proposed...
Conference Abstract

P136 Determinants of Arterial Stiffness in Children Using Population-indexed Anthropometric and Hemodynamic Parameters

Tommy Cai, Alice Meroni, Ahmad Qasem, Mark Butlin, Julian Ayer, David Celermajer, Alberto Avolio, Michael Skilton
Pages: S174 - S174
Background: Arterial stiffness is a significant cardiovascular risk factor. Carotid-femoral pulse wave velocity (cfPWV) is the standard for measuring arterial stiffness, but indices such as central augmentation index (cAIx) and carotid artery elasticity (cE[p]) also correlate to arterial stiffness. Early-life...
Conference Abstract

P137 Reflections Revisited: Reinterpretation Required

Berend Westerhof, Nico Westerhof
Pages: S175 - S175
Introduction: Pressure waveshape derived parameters such as the augmentation index are related to unfavourable cardiovascular events [1]. Wave reflections determine wave shape [2], however, several findings seem to contradict the current views. Current view. The arterial system can be modelled by a tube...
Conference Abstract

P138 Modelling and Simulation of Pressure Re-reflections at the Aortic Valve Using Difference Equations

Bernhard Hametner, Hannah Kastinger, Siegfried Wassertheurer
Pages: S176 - S176
Introduction: The concept of re-reflections of blood pressure waves at the heart has been neglected in most models and is only poorly understood so far. Therefore, the aim of this work was to develop a simple mathematical model which is capable to represent the effects of wave travel, wave reflection...
Conference Abstract

P139 Does Early Life Programming Influence Arterial Stiffness and Central Hemodynamics in Adulthood? Could Birth Cohort Effects be of Importance?

Peter Nilsson, Johannes Sperling
Pages: S177 - S177
Objective: Our aim was to investigate possible associations between birth weight (BW) and adult carotid-femoral Pulse Wave Velocity (cfPWV) and augmentation pressure index (AIx). Design: This study including 1598 participants, 340 elderly subjects and 1258 young-middle aged subjects from the Malmö Offspring...
Conference Abstract

P142 Androgen Receptor Reduced Sensitivity is Associated with Cardiovascular Mortality in Men with Type 2 Diabetes - A 14-year Follow up Study

Adrian Heald, Ghasem Yadegarfar, Mark Livingston, Helene Fachim, Ram Prakash Narayanan, Mark Lunt, Kirk Siddals, Gabriela Cortes, Martin Gibson, Rachelle Donn, Simon Anderson, Geoff Hackett, Hugh Jones
Pages: S178 - S179
Background: Hypogonadism associates with increased cardiovascular morbidity/mortality in type 2 diabetes mellitus (T2DM)[1]. Increasing CAG repeat number within exon 1 of the androgen receptor gene associates with increased androgen receptor resistance/insulin resistance [2]. We here investigated the...
Conference Abstract

P144 Augmentation Index is not a Reliable Measure of Wave Reflections in Patients with Severe Aortic Stenosis

Stamatia Pagoulatou, Nikolaos Stergiopulos, Vasiliki Bikia, Georgios Rovas, Hajo Müller, Stéphane Noble, Dionysios Adamopoulos
Pages: S180 - S180
Background: Augmentation index (AIx) serves as an independent predictor of cardiovascular events and mortality. It is often clinically used as a measure of arterial stiffness and reflections, a practice that was recently challenged. In this work, we sought to investigate the association between AIx and...
Conference Abstract

P145 Central Hemodynamic Response to Lower Body Negative Pressure in Individuals with Down Syndrome

I Thessa, Sang Ouk Wee, Georgios Grigoriadis, Elizabeth Schroeder, Tracy Baynard, Bo Fernhall
Pages: S181 - S181
Introduction: Individuals with Down syndrome (DS) have autonomic dysfunction, which impacts heart rate and blood pressure regulation. Initial evidence also suggests an impaired ability to peripherally vasoconstrict during lower body negative pressure (LBNP). Given the relationship between vessel caliber...
Conference Abstract

P146 The Predictive Role of Arterial Stiffness in the Development of Acute Kidney Injury in Patients Undergoing Surgical Aortic Valve Replacement

Evangelia Sigala, Charalambos Vlachopoulos, Konstantinos Triantafyllou, Andreas Katsaros, Nikolaos Koumallos, Vasilios Lozos, Nikolaos Baikoussis, Ilias Kouerinis, Nikolaos Giakis, Demosthenous Michael, Dimitrios Terentes Printzios, Konstantinos Filis, Dimitrios Tousoulis
Pages: S182 - S182
Purpose/Background/Objectives: Acute kidney injury (AKI) is a serious postoperative complication. Increased arterial stiffness has been shown to be an independent risk factor for cardiovascular events. Our aim was to investigate whether arterial stiffness is a predictor of AKI in patients following surgical...
Conference Abstract

P147 Association Between Inflammatory Markers of Low Intention and Arterial Stiffness

Daniele Brustolim, Lucelia Magalhaes, Yuri Oliveira Mariano, Vinicius Louzada Castro, João Victor Perrone, Joilson Jesus Barreto Júnior, Gabriela Valverde
Pages: S183 - S184
Extracellular and biochemical changes in the vessel contribute to the stiffening, this process is determinant for the increase of the Pulse Wave Velocity (PWV) and subsequent increase of the central and brachial arterial pressures [1,2]. These vascular alterations are denominated of TOD (target organ...
Conference Abstract

P148 The Administration of Green Tea Extract Improves Hemodynamic Parameters, Arterial Stiffness and Renal Function in Patients with Diabetic Nephropathy

Marycruz Barocio, Fernando Grover, Mayra Jiménez, Mariana Larios, Patricia Quezada, Jhonatan Trujillo, Ernesto Cardona, David Cardona, Carlos Ramos
Pages: S185 - S185
Purpose/Background/Objectives: Type 2 Diabetes Mellitus (T2DM) is a disease characterized by macro and microvascular complications, particularly, coronary heart disease, cerebrovascular disease and nephropathy [1–4]. The green tea extract has shown an anti-inflammatory effect (2), so this nutraceutical...
Conference Abstract

P149 The Relationship Between Insulin Resistance Scores Parameters and Chemerin in Diabetic and Obese Patients

Angela Cozma, Adriana Fodor, Vasile Negrean, Dorel Sampelean, Ionut Minciuna, Monica Oltean, Ionela Popovici, Sorina Coste, Alexandra Dadarlat, Dana Pop, Olga Hilda Orasan, Adela-Viviana Sitar-Taut
Pages: S186 - S186
Background: Chemerin represents a recently discovered chemokine influencing adipocyte function, lipolysis, apparently positively associated with insulin resistance. Purpose: To evaluate the relationship between chemerin-insulin resistance scores in obese/diabetic patients. Methods: 88 patients (66...
Conference Abstract

P150 Study of Heamodynamic and Macrocirculation Indices Between Uncontrolled Naïve Hypertensives and Well Controlled Diabetic Patients

Areti Triantafyllou, Nick Koletsos, Konstantina Dipla, Ioanna Zografou, Xristos Avgerinos, Stauros Papadopoulos, Alexandros-Savvas Zafeiridis, Stella Kritikou, Eugenia Gkaliagkousi, Andreas Zafeiridis, Stella Douma
Pages: S187 - S187
Introduction: Both Type II Diabetes mellitus (DM) and hypertension have been associated with an increased risk for cardiovascular disease and linked to impairments in micro- and macrocirculation. However, previous studies examining micro- and macrocirculation in DM mainly include patients with comorbid...
Conference Abstract

P151 Microvascular Dysfunction is Associated with Impaired Beta-cell Function: The Maastricht Study

Wenjie Li, Alfons Houben, Tos Berendschot, Carroll Webers, Abraham Kroon, Marleen van Greevenbroek, Carla van der Kallen, Ronald Henry, Simone Sep, Pieter Dagnelie, Nicolaas Schaper, Simone Eussen, Casper Schalkwijk, Miranda Schram, Coen Stehouwer
Pages: S188 - S188
Background: The pathophysiological mechanism underlying beta-cell dysfunction in type 2 diabetes (T2D) is not fully understood. Recent animal studies suggest that microvascular dysfunction (MVD) may lead to insufficient delivery of oxygen and nutrients to beta-cells as well as an attenuated delivery...
Conference Abstract

P152 Prediction of Death or Heart Failure-related Hospitalizations by Cardio-ankle Vascular Index (CAVI) and CAVI0

Bart Spronck, Jonathan Lee, Garrett Oldland, Mary Jo Obeid, Mahati Paravathaneni, Naga Vaishnavi Gadela, Armghan Ans, Gurpreet Singh, Rushik Bhuva, Scott Akers, Julio Chirinos
Pages: S189 - S190
Background: Arterial stiffness as measured by carotid-femoral pulse wave velocity (PWV) has been shown to predict cardiovascular events [1]. However, PWV is blood pressure (BP) dependent [2,3] leading to the development of cardio-ankle vascular index (CAVI) as a more blood pressure-independent index...
Conference Abstract

P153 Radial-finger Pulse Wave Velocity as a Measure of Microvascular Stiffness: Feasibility and Response to Nitroglycerin

Catherine Fortier, Mohsen Agharazii, Charles-Antoine Garneau, Karine Marquis
Pages: S191 - S191
Background/Objectives: We previously demonstrated a different regional stiffness response of elastic and muscular arteries after the administration of nitroglycerin, leading to an alteration of aortic-brachial stiffness gradient. Regional stiffness of smaller arteries may respond differently to vasodilation...
Conference Abstract

P154 Effect of Vitamin D Deficiency on Insulin Induced Vasodilatation and Receptor Expression in Rat Model of Polycystic Ovary Syndrome

Bálint Bányai, Benko Rita, Tarszabó Róbert, Lajtai Krisztina, Horváth Eszter Mária, Várbíró Szabolcs
Pages: S192 - S192
In polycystic ovary syndrome (PCOS) hyperandrogenism and metabolic dysfunction increase cardiovascular risk. Vitamin D3 deficiency is a common comorbidity in PCOS. Our aim was to examine the alterations of insulin-induced vasodilation and receptor expression in rat aorta in a PCOS model. Methods: Female...